Pharmacology Mentor | Expert insights in Pharmacology

Physiology of the Thyroid Gland

#thyroid drugs Introduction The thyroid gland plays a pivotal role in human physiology, modulating metabolism, growth, and development through the production and secretion of thyroid hormones. These hormones, primarily triiodothyronine (T3) and thyroxine (T4), influence virtually…

Pharmacology Mentor December 27, 2025

General Pharmacology

Dose-response relationships

The dose-response relationship is a fundamental concept in pharmacology that describes how the effects of a drug change with varying doses. This relationship is crucial for understanding drug potency, efficacy,…

Pharmacology Mentor December 27, 2025

General Pharmacology

Drug-Receptor Interactions: Agonists and Antagonists

Drug-receptor interactions refer to the binding of drugs to specific receptors, leading to a biological response. These interactions can either be agonistic or antagonistic. Agonists Agonists are drugs that bind…

Pharmacology Mentor December 27, 2025

General Pharmacology

Drug Potency and Efficacy

Understanding "drug potency" and "drug efficacy" is crucial in pharmacology, as they describe a drug's performance and are often used to compare different drugs. These terms are closely related to…

Pharmacology Mentor December 28, 2025

General Pharmacology

Drug Selectivity, Safety, and Risk-Benefit Ratio

The pharmacological landscape is complex, and drugs often produce a range of effects, both therapeutic and adverse. Understanding these nuances is crucial for clinicians to make informed decisions. This article…

Pharmacology Mentor December 28, 2025

General Pharmacology

Drug Specificity: A Key Factor in Pharmacological Actions

Drug specificity is an important concept in pharmacology that refers to the range of actions a drug can produce. Understanding drug specificity is crucial for healthcare professionals, researchers, and patients…

Pharmacology Mentor March 12, 2024

CVS Pharmacology

Miscellaneous Antiarrhythmic Agents: Adenosine and others

Adenosine Adenosine is antiarrhythmic agent that is widely used for the investigation and management of both narrow complex and, less often, broad complex tachycardias. It produces a transient block in the…

Pharmacology Mentor March 12, 2024

CVS Pharmacology

Class 4 Antiarrhythmic Drugs: Verapamil and Diltiazem

Verapamil and diltiazem are non‑dihydropyridine calcium channel blockers classified as Class IV antiarrhythmics, primarily used to slow atrioventricular (AV) nodal conduction and control ventricular rate in supraventricular tachyarrhythmias such as atrial…

Pharmacology Mentor September 11, 2025

CVS Pharmacology

Antiarrhythmic drugs: Class III – Amiodarone and others

#Amiodarone Structure Class III antiarrhythmics predominantly prolong cardiac repolarization via potassium channel blockade, with amiodarone as the prototypical agent and additional options including dofetilide, sotalol, ibutilide, and dronedarone chosen based on structural…

Pharmacology Mentor December 27, 2025

CVS Pharmacology

Antiarrhythmic drugs: Beta-adrenoceptor-blocking drugs (Class 2)

Introduction Among the diverse categories of drugs used to manage cardiac arrhythmias, beta-adrenoceptor-blocking drugs (beta blockers)—classified as Class 2 antiarrhythmics under the Vaughan Williams scheme—play a pivotal role in controlling aberrant…

Pharmacology Mentor December 28, 2025