Drugs acting on ANS Last updated: 2024/04/15 at 6:45 PM Pharmacology Mentor 148 Views Share 0 Min Read SHARE Welcome to Drugs acting on ANS 1. Drug of choice in treatment of myasthenia gravis is: d-Tubocurarine Hexamethonium Neostigmine Gallamine None 2. Organophosphates act by inhibiting the enzyme acetylcholinesterase. Which type of enzyme inhibitors are they? Uncompetitive and reversible Competitive and reversible Competitive and irreversible Non-competitive and irreversible None 3. Beta blocker having both α and β blocking property is: Sotalol Nadolol Carvedilol Pindolol None 4. Mechanism of action of pralidoxime is: Blockade of ACh receptors Inhibition of breakdown of ACh Reactivation of AChE enzyme Stimulation of ACh receptors None 5. The short acting anticholinesterase drug is: Ectothiophate Edrophonium Dyflos Demecarium None 6. A 35-year-old man was found unconscious. Examination revealed bilateral constricted pupils, bradycardia, excessive sweating and secretion. Most likely cause is: Organophosphate poisoning Opium poisoning Pontine hemorrhage Acute alcohol intoxication None 7. Which of the following alpha-blocker drug is used in the treatment of benign hypertrophy of prostate without producing significant hypotension? Tamsulosin Terazosin Phentolamine Dexazosin None 8. Use of tiotropium is contraindicated in: Bronchial asthma Hypertension Urinary retention Peptic ulcer disease None 9. Antidote for nicotine poisoning is: Atropine sulphate Neostigmine Phentolamine Trimethaphan None 10. Alpha 1a (α1A) adrenergic blocker providing symptomatic relief in BPH is: Tamsulosin Prazosin Doxazosin Tolazoline None 11. Atropine is useful in organophosphate poisoning because it: Reactivates acetylcholinesterase Binds with both nicotinic and muscarinic acetylcholine receptors Is a competitive antagonist of acetylcholine Competes with acetylcholine release None 12. An ultrashort acting β−blocker devoid of partial agonistic or membrane stabilizing action is: Timolol Atenolol Pindolol Esmolol None 13. An 80 kg patient is brought in the causality in shock. Dopamine needs to be started at 10 micro/kg/min rate. A 5 mL vial contains 200 mg of dopamine. Two vials are diluted to a solution of 250 mL with the help of normal saline. Calculate drops per minute required to be administered if 1 mL = 16 drops. 8 32 16 24 None 14. Diagnosis of myasthenia gravis is done by using: Succinylcholine Atropine Edrophonium Neostigmine None 15. Beta blockers are indicated for all of the following conditions EXCEPT: Hypothyroidism Portal hypertension Alcohol withdrawal Performance anxiety None 16. Treatment of choice for anaphylactic shock is: Adenosine 12 mg intravenously Adrenaline 1 mL of 1:10000 by intravenous route Adrenaline 0.5 mL of 1:1000 solution by intramuscular route Atropine 3 mg intravenously None 17. Pilocarpine reduce the intraocular pressure in persons with closed angle glaucoma by: Reducing aqueous humor secretion Relaxing ciliary muscle Contracting iris sphincter muscle Increasing aqueous humor outflow None 18. Beta blockers are not indicated in: Acute CHF Hypertension Chronic CHF Arrhythmia None 19. Ideal drug employed in the preoperative preparation for surgical excision of pheochromocytoma is: Clonidine Reserpine Phenoxybenzamine Atenolol None 20. A child on β2 agonists for treatment of bronchial asthma may exhibit all of the following features EXCEPT: Hypoglycemia Bronchodilation Hypokalemia Tremors None 21. Retinoscopy in 5-year-old is best done with: Homatropine Atropine Tropicamide Cyclopentolate None 22. All of the following are cardioselective beta blockers EXCEPT: Atenolol Esmolol Propranolol Bisoprolol None 23. Major neurotransmitter released at end organ effectors of the sympathic division of the autonomic nervous system is: Adrenaline Dopamine Noradrenaline Acetylcholine None 24. The beta blocker having intrinsic sympathomimetic activity is: Pindolol Propranolol Sotalol Atenolol None 25. Which is the shortest acting mydriatic? Cyclopentolate Atropine Tropicamide Homatropine None 26. A hypertensive patient has heart rate of 50 beats/min and taking tablet atenolol 200 mg/day in divided doses. After anesthesia, heart rate further fell down to 40 beats/min. What will be the appropriate treatment to improve heart rate: IV adrenaline Dobutamine infusion intravenously IV isoprenaline IV atropine None 27. Cholinomimetics are useful in all of the following conditions EXCEPT: Partial heart block Glaucoma Myasthenia gravis Post operative atony of bladder None 28. A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors and red tears. Plasma cholinesterase level was 30% of normal. Most probable Diagnosis is: Organophosphate poisoning Opioid poisoning Pontine hemorrhage Datura/belladonna poisoning None 29. A child presented with history of ingestion of some unknown plant and developed mydriasis, tachycardia, dry mouth, warm skin and delirium. Which of the following group of drugs is likely to be responsible for the symptoms of this child? Sympathomimetic Anticholinergic Opioid Benzodiazepine None 30. Drug of choice for mushroom poisoning is: Carbachol Atropine Physostigmine Adrenaline None 31. Which of the following drug is a long acting beta-2 agonist? Pirbuterol Salmeterol Albuterol Orciprenaline None 32. Acetylcholine is not used commercially because: Costly Rapidly destroyed in the body Long duration of action Crosses blood brain barrier None 33. Which of the following drugs does not cross blood placental barrier? Glycopyrrolate Physostigmime Hyoscine hydro bromide Atropine None 34. Which ONE of the drugs used for atropine toxicity? Flumazenil Physostigmine Naloxone 2-Pralidoxime None 35. A 24-years-old farm worker is rushed to a nearby emergency department after an accidental exposure to parathion. Which of the following drugs can be given to increase the activity of his acetyl cholinesterase: Dimercaprol Atropine Physostigmine Pralidoxime None 36. Neostigmine is not able to cross blood brain barrier because of its: Tertiary structure Primary structure Quarternary structure Secondary structrure None Time's up Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always seek the advice of a healthcare provider with any questions regarding a medical condition. You Might Also Like PHAL6013 practice quiz -2 PHAL6013 practice questions Local Anesthetics Post Lab Quiz – MDSC2203-2023-24 Quiz on Antihyperlipidemics Quiz on Antihypertensives Sign Up For Daily NewsletterBe keep up! 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