Practice Quizzes on Drugs used in GI Disorders Last updated: 2024/04/15 at 6:45 PM Pharmacology Mentor 8 Views Share 0 Min Read SHARE Welcome to your Practice Quizzes on Drugs used in GI Disorders In a case where a 50-year-old male patient diagnosed with Zollinger-Ellison Syndrome does not attain adequate symptomatic control with high-dose proton pump inhibitor (PPI) therapy, additional therapeutic interventions may be required. Which of the following adjunctive treatments may be considered? Prokinetic Agents H2 Receptor Antagonists Bismuth Subsalicylate Antacids Sucralfate None For the management of IBD-associated arthritis, which of the following medications is most commonly used? Infliximab Sulfasalazine Azathioprine Mesalamine Metronidazole None Which antiemetic is commonly used for motion sickness? Haloperidol Scopolamine Ondansetron Metoclopramide Promethazine None In the treatment of peptic ulcer disease, one therapeutic approach involves the use of a medication that forms a protective layer over the ulcer site, safeguarding the area from the corrosive effects of gastric acid and aiding in healing. Which of the following agents employed in the management of peptic ulcer disease exerts its therapeutic effect by forming a protective barrier on the surface of the ulcer? Ranitidine Misoprostol Metronidazole Sucralfate Omeprazole None A patient with migraine-associated nausea would benefit most from which of the following medications? Ondansetron Prochlorperazine Scopolamine Dexamethasone Metoclopramide None Which medication is effective for both the treatment of IBD and prevention of colon cancer in these patients? Cyclosporine Mesalamine Infliximab Metronidazole Azathioprine None For a 45-year-old male patient with a history of peptic ulcer disease who experiences epigastric pain that improves with eating, the therapeutic goal is to provide a medication that can offer a protective coating to the gastric mucosa, thus shielding the ulcerated area from further irritation by gastric acid. In this scenario, the most appropriate medication to achieve this goal is: Esomeprazole Ranitidine Omeprazole Metronidazole Sucralfate None Which antibiotic is recommended as the first-line treatment for severe cholera in adult patients? Metronidazole Azithromycin Amoxicillin Doxycycline Ciprofloxacin None In the pharmacological management of gastroesophageal reflux disease (GERD), which agent is recognized for its ability to augment lower esophageal sphincter (LES) tone, contributing to the mitigation of reflux symptoms? Ranitidine Omeprazole Sucralfate Metoclopramide Aluminum hydroxide None Which medication is used to manage short bowel syndrome in patients with Crohn's disease? Metoclopramide Loperamide Infliximab Sulfasalazine Mesalamine None In the management of hyperemesis gravidarum, which medication is considered safe and effective? Ondansetron Metoclopramide Doxylamine and pyridoxine Scopolamine Aprepitant None Which pharmacological treatment is deemed teratologically safe and thus recommended for the amelioration of gastroesophageal reflux disease (GERD) symptoms in a woman during the second gestational trimester? Metoclopramide Pantoprazole Sucralfate Omeprazole Misoprostol None A patient undergoing radiation therapy experiences nausea. Which of the following drugs is best suited for radiation-induced nausea? Meclizine Lorazepam Scopolamine Ondansetron Aprepitant None Which of the following is a side effect commonly associated with interferon-alpha therapy used in the treatment of hepatitis? Hypoglycemia Hypertension Hyperkalemia Flu-like symptoms Constipation None Which medication is commonly used as a first-line treatment for mild to moderate ulcerative colitis? Metronidazole Prednisone Azathioprine Mesalamine Infliximab None In the context of Zollinger-Ellison Syndrome, where excessive gastrin production leads to recurrent peptic ulcers and gastritis due to increased gastric acid secretion, the pharmacotherapy aims at controlling acid hypersecretion to prevent ulcer formation and related complications. What is the principal objective of pharmacological intervention in a patient diagnosed with Zollinger-Ellison Syndrome? Stimulation of gastric motility Eradication of gastric tumors Increase in gastric pH to 7 Control of gastric acid hypersecretion Complete neutralization of gastric acid None Which of the following antiemetics is most appropriate for treating nausea associated with vertigo? Meclizine Haloperidol Ondansetron Metoclopramide Aprepitant None A 60-year-old woman with a history of rheumatoid arthritis is prescribed a long-term NSAID for pain management. To reduce her risk of developing a peptic ulcer, which of the following medications should be considered? Famotidine Sucralfate Bismuth subsalicylate Misoprostol Ranitidine None A patient with Crohn's disease is experiencing severe symptoms. Which of the following is a preferred treatment option for inducing remission? Diphenoxylate Loperamide Bismuth subsalicylate Ondansetron Infliximab None In the management of a patient with cholera, the predominant clinical feature of which is profuse watery diarrhea leading to severe dehydration, the most vital component of treatment is the prompt and adequate replacement of fluids and electrolytes. What is the paramount therapeutic intervention for a patient suffering from cholera-induced severe dehydration? Antiemetic medication Intravenous fluid replacement Zinc supplementation Oral rehydration salts (ORS) Antibiotic therapy None In the management of peptic ulcer disease, Misoprostol is utilized for its mucoprotective properties, which are mediated through the enhancement of gastric mucus and bicarbonate secretion, as well as the promotion of submucosal blood flow, thereby bolstering the gastric mucosal barrier. Despite its therapeutic benefits, certain clinical situations necessitate the avoidance of Misoprostol due to the risk of adverse effects. Choose the most appropriate contraindication from the options below: by enhancing mucosal blood flow, thereby promoting ulcer healing and preventing ulcer formation. Pregnancy Hypertension Diabetes Mellitus Hyperthyroidism Glaucoma None For a patient diagnosed with an E. coli urinary tract infection and with a known allergy to fluoroquinolones, which of the following therapeutic agents represents a viable alternative for treatment? Erythromycin Co-trimoxazole Vancomycin Metronidazole Clindamycin None Which of the following is a neurokinin-1 receptor antagonist used in the prevention of chemotherapy-induced nausea and vomiting? Lorazepam Prochlorperazine Ondansetron Metoclopramide Aprepitant None Which antiemetic is most effective for preventing chemotherapy-induced nausea and vomiting? Diphenhydramine Ondansetron Dexamethasone Prochlorperazine Metoclopramide None A patient with postoperative nausea and vomiting would benefit most from which of the following medications? Aprepitant Lorazepam Ondansetron Metoclopramide Dexamethasone None Which antiemetic is recommended for a patient with emesis due to gastroenteritis? Aprepitant Promethazine Metoclopramide Lorazepam Ondansetron None In the therapeutic regimen of gastroesophageal reflux disease (GERD), the optimal timing of proton pump inhibitor (PPI) dosing is imperative for maximizing drug efficacy. For a patient diagnosed with GERD to achieve optimal suppression of gastric acid secretion, at what interval should the proton pump inhibitor be administered relative to meals? With meals 30 to 60 minutes prior to a meal Immediately after eating At bedtime Immediately before eating None In the clinical management of uncomplicated enteric fever, the choice of an appropriate first-line antibiotic is essential to ensure efficacy and prevent the development of resistance. Which antibiotic is considered the initial pharmacological treatment of choice for a patient diagnosed with uncomplicated enteric fever? Metronidazole Penicillin Azithromycin Amoxicillin Ciprofloxocin/Ceftriaxone None For a patient experiencing nausea due to gastroparesis, which medication would be most appropriate? Ondansetron Promethazine Dexamethasone Metoclopramide Scopolamine None In managing a patient presenting with sepsis secondary to a severe E. coli infection, what is the most appropriate initial antibiotic strategy? Delayed initiation of antibiotics until culture results are available E) Antibiotic monotherapy Broad-spectrum antibiotics Narrow-spectrum antibiotics Supportive care without antibiotics None Which antiemetic is considered most effective for anticipatory nausea and vomiting due to chemotherapy? Metoclopramide Lorazepam Aprepitant Dexamethasone Ondansetron None Which antimicrobial agent is frequently prescribed as the initial treatment for uncomplicated urinary tract infections predominantly caused by Escherichia coli? Azithromycin Erythromycin Metronidazole Vancomycin Ciprofloxacin None For a pregnant woman diagnosed with enteric fever, the selection of an appropriate antibiotic is crucial to ensure safety for both the mother and the developing fetus. In the treatment of enteric fever for a 25-year-old pregnant patient, which of the following antibiotics is contraindicated due to teratogenic risk or potential harm to the developing fetus? Amoxicillin Cefixime Azithromycin Ceftriaxone Ciprofloxacin None In locales with a high incidence of multi-drug resistant Salmonella typhi, the determination of the most efficacious antibiotic regimen is critical to patient outcomes. Considering the prevalence of multi-drug resistant strains of Salmonella typhi, which antibiotic is currently recognized as the most effective for treatment? Co-trimoxazole Ampicillin Chloramphenicol Azithromycin Ciprofloxacin None Time's up Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always seek the advice of a healthcare provider with any questions regarding a medical condition. 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