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Pharmacokinetics

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magnesium sulfate
Posted inmiscellaneous Pharmacology

Pharmacology of Magnesium Sulfate

Introduction Magnesium is the fourth most abundant cation in the human body and plays a critical role in numerous physiological processes. Magnesium sulfate (MgSO4) is an inorganic salt that has…
Read More Pharmacology of Magnesium Sulfate
Posted by Pharmacology Mentor December 27, 2025
Procainamide
Posted inCVS Pharmacology

Antiarrhythmic drugs: Procainamide (Class 1A)

Procainamide is a Class IA antiarrhythmic that blocks fast INaINa channels and prolongs repolarization via its active metabolite N-acetylprocainamide (NAPA), making it useful for acute management of a variety of ventricular and…
Read More Antiarrhythmic drugs: Procainamide (Class 1A)
Posted by Pharmacology Mentor December 28, 2025
Carbonic Anhydrase Inhibitors
Posted inCVS Pharmacology

Pharmacology of Carbonic Anhydrase Inhibitors

I. Introduction and Class Overview Carbonic anhydrase inhibitors (CAIs) are a class of drugs that reversibly inhibit the enzyme carbonic anhydrase, thereby interfering with HCOโ‚ƒโป (bicarbonate) reabsorption and decreasing hydrogen…
Read More Pharmacology of Carbonic Anhydrase Inhibitors
Posted by Pharmacology Mentor December 28, 2025
Osmotic Diuretics
Posted inCVS Pharmacology

Pharmacology of Osmotic Diuretics

Mechanism of Action: Osmotic diuretics work by increasing the osmolarity of the filtrate in the renal tubules. The glomerulus filters them but does not reabsorb them, creating an osmotic gradient…
Read More Pharmacology of Osmotic Diuretics
Posted by Pharmacology Mentor December 28, 2025
Potassium-sparing diuretics
Posted inCVS Pharmacology

Pharmacology of Potassium-Sparing Diuretics

Potassium-sparing diuretics are a class of diuretic medications that increase diuresis (urine production) while conserving potassium, contrasting with thiazide and loop diuretics that promote potassium loss. They are used primarily…
Read More Pharmacology of Potassium-Sparing Diuretics
Posted by Pharmacology Mentor December 28, 2025
loop diuretics
Posted inCVS Pharmacology

Pharmacology of Loop Diuretics

Introduction Loop diuretics are a cornerstone of therapy in conditions where rapid and potent diuresis (urine output) is required. By inhibiting sodium and chloride reabsorption in the thick ascending limb…
Read More Pharmacology of Loop Diuretics
Posted by Pharmacology Mentor December 28, 2025
first-order vs zero-order kinetics
Posted inGeneral Pharmacology

First-Order vs. Zero-Order Kinetics: What You Need to Know

Zero-Order Kinetics Definition: In zero-order kinetics, the rate of drug elimination is constant and does not depend on the drug concentration. This is often seen with drugs that saturate the…
Read More First-Order vs. Zero-Order Kinetics: What You Need to Know
Posted by Pharmacology Mentor September 3, 2023
Anticancer drugs
Posted inPharmacology

The Comprehensive Guide to Anticancer Drugs: What You Need to Know

Introduction to Anticancer Drugs: Anticancer drugs are medications that inhibit the development and spread of cancerous cells. They achieve this by interfering with the DNA and RNA that cause cell…
Read More The Comprehensive Guide to Anticancer Drugs: What You Need to Know
Posted by anonymous December 28, 2025
Sodium Channel Blockers
Posted inNeuropharmacology Pharmacology

Sodium Channel Blockers (SCBs)

Introduction Sodium (Naโบ) channels are integral membrane proteins responsible for the rapid upstroke (phase 0) of the action potential in excitable cells such as neurons and cardiomyocytes. By selectively perming…
Read More Sodium Channel Blockers (SCBs)
Posted by Pharmacology Mentor January 26, 2025
H2 Receptor Antagonists
Posted inGI

Pharmacology of H2 Receptor Antagonists

Histamine H2 receptor antagonists are competitive blockers of gastric parietal-cell H2 receptors that suppress basal and stimulated acid secretion and are used for GERD, peptic ulcer disease, hypersecretory states, and…
Read More Pharmacology of H2 Receptor Antagonists
Posted by Pharmacology Mentor October 6, 2025

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