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Sympathomimetics/Adrenergic agonists

1 · Introduction Sympathomimetic agents—or adrenergic agonists—comprise a pharmacological super-family that mimics or amplifies the actions of endogenous catecholamines (noradrenaline, adrenaline and dopamine) at α1, α2, β1, β2, β3 and…

Pharmacology Mentor April 8, 2023

General Pharmacology

Clinical Pharmacokinetics: From Principles to Individualized Dosing

Clinical pharmacokinetics (PK) is the science of quantifying how drugs are absorbed, distributed, metabolized, and excreted in humans, and applying that knowledge to optimize therapy for individual patients. Its goals…

Pharmacology Mentor April 3, 2023

General Pharmacology

Adverse Drug Reactions – ABCDE classification

1 · Introduction Drugs are double-edged swords: while they alleviate symptoms, modify disease course and often save lives, they also generate harm. This harm can arise from adverse drug reactions…

Pharmacology Mentor April 3, 2023

General Pharmacology

Drug Interactions

Introduction Drug interactions are a central topic in clinical pharmacology, profoundly impacting therapeutic efficacy, safety, and patient outcomes. While drug interactions are often discussed in terms of adverse effects or…

Pharmacology Mentor April 3, 2023

General Pharmacology

Pharmacodynamics: Understanding What Drug Does to the Body

Pharmacodynamics is a branch of pharmacology that focuses on the study of how drugs interact with the body at the molecular, cellular, and systemic levels to produce their effects. It…

Pharmacology Mentor April 3, 2023

General Pharmacology

Pharmacokinetics – What the body does to Drug?

Pharmacokinetics, derived from the Greek words 'pharmakon' meaning drug, and 'kinesis' meaning movement, is the science that elucidates what the body does to a drug following administration. Pharmacokinetics is the…

Pharmacology Mentor April 3, 2023

Clinical Pharmacology Pharmacology

The Comprehensive Guide to Drug Discovery, Development, and Clinical Trials: Everything You Need to Know

Drug discovery and development is an intricate and multifaceted process that encompasses identifying, designing, and testing prospective new drugs. The primary objective is to discover secure and effective treatments for…

Pharmacology Mentor April 2, 2023

General Pharmacology

Chapters and Topics in General Pharmacology

Introduction to General Pharmacology General pharmacology covers the fundamental principles of pharmacology, including Drug discovery and development, Souces of Drugs, Dosage forms, Routes of drug administration, Pharmacokinetics, Clinical Pharmacokinetics, Pharmacodynamics, Drug interactions and Adverse drug reactions…

Pharmacology Mentor April 2, 2023

General Pharmacology

Factors Affecting Oral Drug Absorption and its Bioavailability

Oral drug absorption is a critical process that determines the efficacy and safety of a medication. The bioavailability of a drug depends on various factors, including physical properties, dosage forms,…

Pharmacology Mentor March 31, 2023

Drugs acting on Autonomic Nervous System (ANS)

ANS Pharmacology

Adrenaline/Epinephrine-Induced Fight, Flight and Fright Response

Understanding the action of drugs on the autonomic nervous system (ANS) can be simplified by drawing a comparison with the adrenaline/epinephrine-induced fight, flight, and fright response. This response, also known…

Pharmacology Mentor March 28, 2023

Sympathomimetics/Adrenergic agonists

Clinical Pharmacokinetics: From Principles to Individualized Dosing

Adverse Drug Reactions – ABCDE classification

Drug Interactions

Pharmacodynamics: Understanding What Drug Does to the Body

Pharmacokinetics – What the body does to Drug?

The Comprehensive Guide to Drug Discovery, Development, and Clinical Trials: Everything You Need to Know

Chapters and Topics in General Pharmacology

Factors Affecting Oral Drug Absorption and its Bioavailability

Adrenaline/Epinephrine-Induced Fight, Flight and Fright Response

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