Endocrine

Linzagolix Pharmacology and Recent Advancements

Introduction Linzagolix, brand named Yselty®, is a selective, orally administered, non-peptide small molecule gonadotrophin-releasing hormone (GnRH) receptor antagonist developed by Kissei Pharmaceutical, aimed at treating...

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Antimicrobial

Pharmacology of Albendazole

Introduction Albendazole is a broad-spectrum anthelmintic widely used in both human and veterinary medicine. First introduced in the 1970s, it has since become an essential...

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ANS

Pharmacolgy of Atropine: antimuscarinic agent

Introduction Atropine is a naturally occurring anticholinergic agent extracted from various plants of the Solanaceae family, most notably Atropa belladonna (deadly nightshade). Renowned for blocking...

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ANS

Pharmacology of Pilocarpine: a muscarinic receptor agonist

Introduction Pilocarpine is a naturally occurring alkaloid primarily obtained from the leaves of the Pilocarpus genus, particularly Pilocarpus microphyllus and Pilocarpus jaborandi. Classified as a...

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ANS

Pharmacology of Anticholinergics: Atropine

Introduction Atropine—the prototypical naturally occurring belladonna alkaloid—has been used in medicine for well over a century. Extracted chiefly from Atropa belladonna (deadly night-shade), it remains indispensable...

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Endocrine

Pharmacology of Gonadotropin-releasing hormone (GnRH) antagonists

Introduction Gonadotropin-releasing hormone (GnRH) antagonists have redefined several aspects of endocrine and reproductive medicine by offering a more direct and immediate means of suppressing the hypothalamic-pituitary-gonadal...

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Endocrine

Gonadotropin-releasing hormone (GnRH) agonists

Gonadotropin-releasing hormone (GnRH) agonists are synthetic peptide analogues of native GnRH engineered to resist enzymatic degradation and to produce sustained receptor activation that ultimately suppresses...

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Endocrine

Pharmacology of Danazol: a synthetic steroid

Introduction and Chemical Nature Danazol is a synthetic isoxazole derivative of 17α-ethinyl testosterone. It was developed for its unique endocrine properties and mild androgenic activity, making...

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Pharmacology

Pharmacology of Testosterone

Introduction Testosterone is a key steroid hormone primarily secreted by the testes in males and, to a lesser extent, by the ovaries in females and the...

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Antimicrobial

Pharmacology of Quinupristin-dalfopristin

Introduction Quinupristin-dalfopristin is a parenteral antibiotic combination belonging to the streptogramin class. It arose as a potent therapeutic alternative for managing resistant Gram-positive bacterial infections, particularly...

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