Hematology

📋 Table of Contents Introduction to Anticoagulants The Coagulation Cascade – A Quick Review Classification of Anticoagulants Unfractionated Heparin (UFH) Low Molecular Weight Heparins (LMWH) Warfarin & Coumarin Derivatives Direct Oral Anticoagulants (DOACs) Other Anticoagulants Comparative Analysis Monitoring & Reversal Clinical Scenarios & Guidelines Drug Interactions Special Populations Key Takeaways 🩸 1. Introduction to Anticoagulants … Read more

Introduction Fibrinolytics—also known as thrombolytics—are a specialized class of pharmacological agents that dissolve blood clots (thrombi) by catalyzing the conversion of plasminogen to plasmin, the main fibrinolytic enzyme. These drugs are crucial in the acute management of life-threatening conditions such as acute myocardial infarction (AMI), acute ischemic stroke, and massive pulmonary embolism. By reinstating blood … Read more

Introduction Anticoagulants constitute an essential class of drugs used to inhibit blood coagulation, ultimately preventing or treating thromboembolic disorders such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in atrial fibrillation (AF). By targeting specific elements in the clotting cascade—whether upstream or downstream—anticoagulants forestall the formation, propagation, or recurrence of harmful clots. However, because … Read more