h. pylori | Pharmacology Mentor

Peptic Ulcer Disease (PUD) – A brief note

January 28, 2026November 21, 2023 by Pharmacology Mentor

Introduction Peptic Ulcer Disease (PUD) is a gastrointestinal disorder characterized by sores or lesions in the lining of the stomach or duodenum. It is a significant health concern worldwide, affecting a broad demographic. Pathophysiology Peptic ulcers result from an imbalance between mucosal defensive factors (like mucus and bicarbonate secretion) and aggressive factors (such as gastric … Read more

Helicobacter pylori Infection and Treatment

December 28, 2025November 21, 2023 by Pharmacology Mentor

Introduction Helicobacter pylori (H. pylori) is a spiral-shaped, gram-negative bacterium that colonizes the human stomach and duodenum. First identified in the early 1980s, this organism quickly garnered attention due to its critical role in the pathogenesis of peptic ulcer disease, chronic gastritis, and certain types of gastric malignancies, notably gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) … Read more