Pharmacology of Rivaroxaban

Pharmacology of Rivaroxaban

Introduction Rivaroxaban is an oral direct Factor Xa inhibitor widely used for the prevention and treatment of thromboembolic disorders. Developed as part of a newer generation of target-specific oral anticoagulants (TSOACs) or direct oral anticoagulants (DOACs), rivaroxaban offers several advantages over older agents such as warfarin and low-molecular-weight heparins. Marked by high specificity for Factor Xa, rivaroxaban effectively prevents conversion of prothrombin (Factor II) to thrombin (Factor IIa) in … Read more