By using this site, you agree to the Privacy Policy and Terms of Use.

Home
Bookmarks
Pages
Quizzes
Blog
Chapters
- General
- CVS
- Antimicrobial
- Neuropharmacology
- ANS
- PNS
- GI
- Endocrine
- Hematology
- miscellaneous
Drug Monographs

Advertise

Reading: Anticoagulants, antiplatelet drugs and fibrinolytics

Notification Show More

Font ResizerAa

Home
Blog
Bookmarks
Terms and conditions
Submit a Topic or Chapter
Ask for a topic
Copyright Statement
Contact
Quizzes
About

Have an existing account? Sign In

Advertise

Pharmacology Mentor > Anticoagulants, antiplatelet drugs and fibrinolytics

Anticoagulants, antiplatelet drugs and fibrinolytics

Last updated: 2024/04/15 at 6:46 PM

Pharmacology Mentor 39 Views

0 Min Read

Quiz on Anticoagulants, antiplatelet drugs and fibrinolytics:

A diabetic female on INH and rifampicin for TB developed DVT. She was started on warfarin, PT is not raised, and next step should be:

Use LMW heparin

Increase the dose of warfarin

Switch ethambutol for rifampicin

Replace warfarin with acenocoumarin

None

Anticoagulant of choice for heparin induced thrombocytopenia is?

Plasminogen

Aprotinin

Lepirudin

Abciximab

None

Which of the following substance can be used as anantidote to fibrinolytics?

Alteplase

Epsilon Amino Caproic Acid

Dabigatran

Protamine

None

Mechanism of action of aspirin as antiplatelet drug is its inhibitory action on?

Thromboxane A2

Phospholipase C

PGF 2 alpha

Prostacyclins

None

The most common adverse effect with ticlopidine is:

Diarrhea

Thrombocytopenic purpura

Neutropenia

Hemorrhage

None

Recent oral direct thrombin inhibitor which can be used for prevention of stroke is:

Dabigatran

Lepirudin

Saxagliptin

Ximelagatran

None

Aspirin is not given in a patient who is already on heparin because aspirin causes:

Platelet dysfunction

Aspirin inhibits the action of heparin

Therapy of heparin cannot be monitored

Enhanced hypersensitivity of heparin

None

The anticoagulant of choice in pregnancy is:

Heparin

Dicumarol

Phenindione

Warfarin

None

In low dose aspirin acts on:

Cyclooxygenase

PGI2 synthase

Thromboxane A2 synthase

Lipoxygenase

None

10.

Oral anticoagulants are monitored by:

Bleeding time (BT)

Partial thromboplastin time (PTT)

Prothrombin time (PT)

Coagulation time (CT)

None

11.

Which of the following drug is NOT a GpIIb/IIIa antagonist?

Prasugrel

Tirofiban

Abciximab

Eptifibatide

None

12.

Mechanism of action of clopidogrel is:

Phosphodiesterase inhibition

GP IIb/IIIa inhibition

Thromboxane A2 inhibition

Inhibit ADP mediated cAMP activation

None

13.

Ticlopidine act by:

Decreasing ADP mediated cAMP activation

GP IIb/IIIa antagonist

Inhibiting COX enzyme irreversibly

Phosphodiesterase inhibition

None

14.

Apixaban is a new drug that acts by:

Activating plasminogen

Inhibiting coagulation factor Xa

Inhibiting TNF alpha

Inhibiting platelet aggregation

None

15.

As compared to unfractionated heparin, low molecular weight heparins:

Predispose to a higher risk of osteopenia

Require more frequent laboratory monitoring

Can be given to patients with heparin induced thrombocytopenia

Are absorbed more uniformly when given subcutaneously

None

16.

Abciximab is:

Antibody against Ib/IX receptors

Adenosine inhibitor

Antibody against Ilb/Illa receptors

Topoisomerase inhibitor

None

17.

A patient of thrombosis of veins has been receiving coumarin therapy for three years. Recently she developed bleeding tendency. How will you reverse the effect of coumarin therapy?

Vit K injection

Protamine injection

Whole blood transfusion

Infusion of fibrinogen

None

18.

Aspirin prolongs bleeding by inhibiting the synthesis of which of the following?

Adenosine receptors

Thromboxane A2

Prostacyclin

Cyclic AMP

None

19.

Antidote of fibrinolytic drugs is:

Heparin

Alteplase

Epsilon amino caproic acid

Protamine

None

20.

Drug used in heparin overdose is:

Protamine sulfate

Ticlopidine

Clopidogrel

Phylloquinone

None

21.

Glycoprotein IIb/IIIa receptor antagonist is:

Tranexamic acid

Ticlopidine

Abciximab

Clopidogrel

None

22.

LMW heparin is preferred over unfractionated heparin because:

LMW heparin has consistent bioavailability

LMW heparin directly inhibits thrombin whereas unfractionated heparin acts via activation of antithrombin

LMW heparin can be given subcutaneously as well as orally

LMW heparins have lesser risk of causing bleeding

None

1 out of 22

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Anticoagulants, antiplatelet drugs and fibrinolytics and are not a comprehensive assessment of the subject.

Stop Timer

Time's up

Are you sure you want to submit this quiz?

Time is Up!

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always seek the advice of a healthcare provider with any questions regarding a medical condition.

Sign Up For Daily Newsletter

Be keep up! Get the latest breaking news delivered straight to your inbox.

Email address:

Leave this field empty if you're human:

By signing up, you agree to our Terms of Use and acknowledge the data practices in our Privacy Policy. You may unsubscribe at any time.

Share This Article

Facebook Twitter Copy Link Print

Previous Article NSAIDs

Next Article Antimicrobial Chemotherapy – Antibacterials

Leave a review Leave a review

Leave a review Cancel reply

Your email address will not be published. Required fields are marked *

Please select a rating! Your Rating

Your comment *

Your name *

Your Email *

Your website

Save my name, email, and website in this browser for the next time I comment.

Yes, add me to your mailing list

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Latest Articles

Stay Connected

Facebook Like

Pharmacology Mentor is dedicated to serving as a useful resource for as many different types of users as possible, including students, researchers, healthcare professionals, and anyone interested in understanding pharmacology.

Quick Link

Terms and conditions
Copyright Statement
Privacy Policy
Ask for a topic
Submit a Topic or Chapter
Contact

Top Categories

Pharmacology
Antimicrobial
Neuropharmacology
Endocrine
Reproductive System
miscellaneous

Sign Up for Our Newsletter

Subscribe to our newsletter to get our newest articles instantly!

Email address:

Leave this field empty if you're human: