Antimicrobial chemotherapy - Quizzes| Pharmacology Mentor

ANTIBACTERIALS

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ANTIVIRAL AND ANTIFUNGAL DRUGS

Quiz on Antimicrobial Chemotherapy - Antiviral and antifungal drugs:

Which drug would treat both dermatophytosis and candidal infections?

Griseofulvin

Nystatin

Ketoconazole

Tolnaftate

None

Enfuvirtide belongs to the class of:

Fusion inhibitors

Nucleotide reverse transcriptase inhibitors

Protease inhibitors

Gp 120 inhibitors

None

Drug of choice in herpes simplex encephalitis is:

Amantadine

Vidarabine

Acyclovir

Interferon

None

Which of the following is most common side effect of zidovudine?

Peripheral neuropathy

Anemia

Lactic acidosis

None

Drug of choice for herpes simplex keratitis is:

Interferon

Ganciclovir

Acyclovir

Amantadine

None

Pancreatitis is a common complication of which one of the following:

Stavudine

Zalcitabine

Zidovudine

Didanosine

None

Following drugs act against HIV-2 except:

Efavirenz

Zalcitabine

Ritonavir

Tenofovir

None

Mechanism of action of protease inhibitors is:

Prevents translation of viral RNA

Inhibits proviral RNA synthesis

Causes apoptosis of the affected cells

Prevents maturation of new viral particles

None

Which of the following anti-metabolites act as an antifungal agent?

Chlorambucil

Paclitaxel

5-Flucytosine (5 FC)

Decarbazine

None

10.

Treatment of choice for coccidiodomycosis is:

Flucytosine

Amphotericin

Griseofulvin

Fluconazole

None

11.

Mechanism of action of oseltamivir is:

Neuraminidase inhibitor

Block DNA dependent RNA polymerase

Blocks M2 protein

Apoptosis of respiratory epithelial cells

None

12.

Drugs that can be used to treat candida infection are all EXCEPT:

Ketoconazole

Amphotericin

Griseofulvin

Nystatin

None

13.

Amphotericin B toxicity can be reduced by?

Incorporating it in liposomal complex

Injecting the drug with dextrose

Combining with fluconazole

Combining with flucytosine

None

14.

A person is being treated for Human Immunodeficiency Virus-1. He developed hypertriglyceridemia and hypercholesterolemia. Most likely drug implicated for these adverse effects is:

Ritonavir

Raltegravir

Didanosine

Efavirenz

None

15.

Drug of choice for acyclovir resistant herpes is:

Foscarnet

Gancyclovir

Valacyclovir

Cidofovir

None

16.

Which of the following drugs is used to prevent HIV transmission from an HIV positive pregnant mother to child? (AIIMS Nov. 2011)

Stavudine

Lamivudine

Nevirapine

Didanosine

None

17.

Liposomal amphotericin B has the following advantage over conventional amphotericin B:

Lesser nephrotoxicity

Once a week administration

Lesser cost

Absence of infusional toxicity

None

18.

Drug of choice for herpes simplex virus infection is:

Acyclovir

Indinavir

Ribavarin

Zidovudine

None

19.

The minimum period required for post-exposure chemoprophylaxis for HIV is:

4 weeks

12 weeks

8 weeks

6 weeks

None

20.

Which of the following is oral drug for treatment of hepatitis C?

Lamivudine

Ledipasvir

Ribamivir

Peg-interferon

None

21.

Mechanism of action of terbinafine is?

Binds to ergosterol

Inhibition of ergosterol synthesis

Prevents formation of purine

Inhition of microtubule formation

None

22.

Drug of choice for chronic hepatitis –B is:

Lamivudine

IFN-alpha

Ribavirin

Zidovudine

None

23.

Which of the following has poorest oral bioavailability?

Amantadine

Rimantidine

Oseltamivir

Zanamivir

None

24.

Drug causing maximum peripheral neuropathy is:

Zidovudine

Didanosine

Stavudine

Lamivudine

None

25.

The antimicrobial agent which inhibits the ergosterol biosynthesis is:

Amphotericin B

Fluconazole

Griseofulvin

5-Flucytosine

None

26.

The drug used to treat acyclovir resistant Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV) infection is:

Abacavir

Ganciclovir

Foscarnet

Valacyclovir

None

27.

All of the following are common adverse effects of HAART therapy except:

Optic neuritis

Steatosis

Increased cholesterol

Lipodytrophy

None

28.

A diabetic patient presents with fungal infection of sinuses and peri-orbital region with significant visual impairment. The best drug for treatment of this patient is:

Ketoconazole

Itraconazole

Broad spectrum antibiotics

Amphotericin B

None

1 out of 28

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antiviral Drugs & Antifungal Drugs and are not a comprehensive assessment of the subject.

Time's up

ANTIMALARIAL DRUGS

Quiz on Antimicrobial Chemotherapy - Antimalarial Drugs:

The development of resistance to conventional treatment has led WHO to recommend the use of combination therapies containing artemisinin derivative (artemisinin-based combination therapies also known as ACTs). All of the following combination therapies are recommended if such resistance is suspected, except:

Artemether plus lumefantrine

Artesunate plus quinine

Artesunate plus pyrimethamine-sulfadoxine

Artesunate plus mefloquine

None

Drug of choice in a patient with severe complicated falciparum malaria is:

Quinine

Chloroquine

Artemether

Artesunate

None

Choose the drug whose single oral dose affords clinical cure of uncomplicated malaria caused by chloroquine sensitive/resistant P. falciparum as well as P. vivax:

Proguanil

Quinine

Mefloquine

Artesunate

None

Which antimalarial drug is known to cause neuropsychiatric adverse reaction?

Artesunate

Quinine

Mefloquine

Artimisnin

None

Chloroquine is given as 600 mg loading dose because:

It is rapidly absorbed

It has increased tissue binding

It is rapidly eliminated

It is rapidly metabolized

None

Absorption of which of the following anti-malarial drug increases with food intake?

Mefloquine

Lumefantrine

Chloroquine

Amodiaquine

None

Which of the following antimalarial drugs is a slow acting schizonticide?

Pyrimethamine

Mefloquine

Artemether

Quinine

None

First line drug for falciparum malaria in pregnancy is:

Primaquine

Chloroquine

Quinine

Tetracycline

None

Radical cure of Plasmodium vivax is by:

Artesunate

Primaquine

Tetracycline

Chloroquine

None

10.

Chemoprophylaxis in an Englishman visiting chloroquine and mefloquine resistant malaria region is done with:

Hydroxychloroquine

Doxycycline

Primaquine

Amodiaquine

None

11.

Which one of the following antimalarial drugs is safe for use in pregnancy?

Atovaquone

Proguanil

Tetracycline

Primaquine

None

12.

Radical cure is required for malaria caused by:

P. falciparum and P. vivax

P. vivax and P. malariae

P. falciparum and P. malariae

P. vivax and P. ovale

None

13.

Which of the following can cause hypoglycemia in a patient of severe cerebral malaria on treatment?

Chloroquine

Halofantrine

Quinine

Mefloquine

None

14.

Tissue schizontocide which prevents relapse of vivax malaria is:

Pyrimethamine

Primaquine

Quinine

Chloroquine

None

15.

Drug of choice for treatment of malaria due to P. vivax in a 25 year old pregnant female is:

Quinine

Primaquine

Chloroquine

Sulfadoxine-pyrimethamine

None

16.

Which one of the following drug may be used for prevention of relapse of P. vivax infection:

Primaquine

Chloroquine

Atovaquone

Tetracycline

None

17.

Drug of choice for treatment of chloroquine resistant falciparum malaria is:

Quinine

Pyrimethamine

Chloroquine

Primaquine

None

18.

Drug of choice for the treatment of a pregnant woman with P vivax malaria is:

Paracetamol

Chloroquine

Quinine

Artemether

None

19.

Drug of choice for chloroquine resistant malaria in pregnancy is:

Artemisinin

Mefloquine

Quinine

Sulphadoxine + pyrimethamine

None

20.

Which of the following drugs can be used for the treatment of chloroquine resistant malaria in children?

Clindamycin

Tetracycline

Doxycycline

Chloroquine

None

1 out of 20

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antimalarial Drugs and are not a comprehensive assessment of the subject.

Time's up

ANTIPROTOZOAL AND ANTIHELMINTHIC DRUGS

Quiz on Antimicrobial Chemotherapy: Antiprotozoal and antihelminthic drugs:

Metronidazole is effective in all of the following conditions except:

Giardiasis

Neurocysticercosis

Pseudomembranous colitis

Amebic liver abscess

None

The drug of choice for schistosomiasis is:

Albendazole

Triclabendazole

Metronidazole

Praziquantel

None

Which of the following drug causes flaccid paralysis of ascaris?

Pyrantel pamoate

Ivermectin

Piperazine

Albendazole

None

A female presented with frothy, greenish vaginal discharge with a musty smell. On examination ‘strawberry vagina’ was noted. A diagnosis of trichomonas vaginalis was made. Drug of choice is:

Erythromycin

Metronidazole

Tetracycline

Fluconazole

None

Drug of choice for medical treatment of hydatid cyst of liver is:

Albendazole

Ivermectin

Thiabendazole

Praziquantel

None

Bull’s eye retinopathy is seen in:

Chloroquine

Ethambutol

Steroids

Methanol

None

Drug of choice for kala-azar is:

Pentamidine

Sodium stibogluconate

Amphotericin B

Penicillin

None

Round worm infection is best treated with:

Albendazol

Metronidazole

Pyrantel pamoate

Mebendazole

None

Drug commonly used in the treatment of echinococosis is:

Ivermectin

Pyrental prermeated

Metronidazole

Albendazole

None

10.

Albendazole is effective against all of the following except:

Tapeworm

Pinworm

Roundworm

Hookworm

None

11.

Amphotericin B produce antifungal action by acting on:

Cell wall

Ribosome

Nucleic acid

Cell membrane

None

12.

Which of the following is not used as treatment for lymphatic filariasis?

Diethyl carbamazine

Albendazole

Praziquantel

Ivermectin

None

13.

DEC (Di-ethyl-carbamazine) is used for the treatment of:

Schistosomiasis

Taeniasis

Filariasis

Dracunculiasis

None

14.

Scabies can be effectively treated systemically by:

Permethrin

Ivermectin

Psoralens

Contrimoxazole

None

15.

Disulfiram like interaction with alcohol is seen with all of the following drugs EXCEPT:

Metronidazole

Satranidazole

Griseofulvin

Cefoperazone

None

16.

Ivermectin is used for the treatment of:

Hookworm infestation

Teniasis

Ascariasis

Filariasis

None

17.

All of these are used in the treatment of visceral leishmaniasis except:

Paromomycin

Hydroxychloroquine

Sitamaquine

Miltefosine

None

18.

Drug of choice for hookworm infestation is:

Bephenium hydroxynaphthoate

Albendazole

Piperazine citrate

Mebendazole

None

19.

Drug of choice for neurocysticercosis is:

Praziquantel

Levamisole

Albendazole

Piperazine

None

1 out of 19

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antiprotozoal & antihelminthic drugs and are not a comprehensive assessment of the subject.

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How to cite this page - Vancouver Style

Mentor, Pharmacology. PRACTICE QUIZZES on antimicrobial chemotherapy. Pharmacology Mentor. Available from: https://pharmacologymentor.com/practice-quizzes-on-antimicrobial-chemotherapy/. Accessed on December 18, 2025 at 00:47.

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PRACTICE QUIZZES on antimicrobial chemotherapy

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