GI | Pharmacology Mentor

Pharmacology of antiemetic drugs

Introduction Nausea and vomiting are protective reflexes designed to prevent the ingestion or continued digestion of harmful toxins. However, when severe, they can significantly deteriorate patient comfort, compromise treatment adherence,…

Pharmacology Mentor August 7, 2023

landscape image on mucosal protective agents

Pharmacology of Mucosal Protective Agents

Introduction Peptic ulcer disease, gastritis, gastroesophageal reflux disease (GERD), and other erosive conditions of the gastrointestinal (GI) tract rank among the most common and debilitating ailments worldwide. In managing these…

Pharmacology Mentor August 7, 2023

Pharmacology of Antacids

Introduction Antacids represent one of the oldest and most commonly used groups of medications for gastrointestinal acidity-related disorders. By chemically neutralizing excessive gastric acid, antacids rapidly relieve symptoms such as heartburn, epigastric…

Pharmacology Mentor August 7, 2023

Pharmacology of H2 Receptor Antagonists

Histamine H2 receptor antagonists are competitive blockers of gastric parietal-cell H2 receptors that suppress basal and stimulated acid secretion and are used for GERD, peptic ulcer disease, hypersecretory states, and…

Pharmacology Mentor August 7, 2023

Drugs Used for Peptic Ulcer Disease (PUD)

Overview Peptic ulcer disease (PUD) encompasses ulceration of the gastric or duodenal mucosa due to an imbalance between aggressive factors (gastric acid, pepsin, Helicobacter pylori, bile, and nonsteroidal anti-inflammatory drugs…

Pharmacology Mentor August 5, 2023

Pharmacology of Proton Pump Inhibitors

Introduction Proton pump inhibitors (PPIs) have revolutionized the management of acid-related gastrointestinal (GI) disorders by rendering potent and long-lasting suppression of gastric acid secretion. Introduced in the late twentieth century, PPIs—exemplified by omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, and dexlansoprazole—effectively mitigate gastric hyperacidity,…

Pharmacology Mentor August 4, 2023

Pharmacology of antiemetic drugs

Pharmacology of Mucosal Protective Agents

Pharmacology of Antacids

Pharmacology of H2 Receptor Antagonists

Drugs Used for Peptic Ulcer Disease (PUD)

Pharmacology of Proton Pump Inhibitors

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