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Antimicrobial

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antiretroviral drugs
Posted inAntimicrobial Pharmacology

Pharmacology of Antiviral Drugs

Introduction Antiviral pharmacology has advanced from the single-agent era of idoxuridine to a modern arsenal including polymerase terminators, protease blockers, monoclonal antibodies, and host-directed entry inhibitors. Because viruses are obligate intracellular…
Read More Pharmacology of Antiviral Drugs
Posted by Pharmacology Mentor May 1, 2025
broad-spectrum antibiotics - tetracyclines
Posted inAntimicrobial Pharmacology

Broad spectrum antibiotics – Tetracyclines and Chloramphenicol

Introduction Broad-spectrum antibiotics stand at the forefront of infectious disease management, enabling healthcare professionals to effectively target a wide variety of bacterial pathogens without waiting for definitive culture results. Within…
Read More Broad spectrum antibiotics – Tetracyclines and Chloramphenicol
Posted by Pharmacology Mentor March 28, 2025
Tuberculosis
Posted inAntimicrobial Pharmacology

Pharmacotherapy of Tuberculosis (TB)

Introduction Tuberculosis (TB) is a potentially severe infectious disease caused primarily by the bacterium Mycobacterium tuberculosis. While TB most commonly affects the lungs (pulmonary tuberculosis), it can also spread to…
Read More Pharmacotherapy of Tuberculosis (TB)
Posted by Pharmacology Mentor January 18, 2025
Tetracyclines
Posted inAntimicrobial Pharmacology

Pharmacology of Tetracyclines

INTRODUCTION Tetracyclines are a class of broad-spectrum antibiotics initially discovered in the late 1940s as natural products of Streptomyces species. They quickly gained wide clinical use due to their efficacy…
Read More Pharmacology of Tetracyclines
Posted by Pharmacology Mentor January 6, 2025
antiretroviral drugs
Posted inAntimicrobial Featured Pharmacology

Pharmacology of antiretroviral drugs

INTRODUCTION The advent of effective antiretroviral therapy (ART) represents one of the most significant milestones in contemporary medicine, radically transforming human immunodeficiency virus (HIV) infection from a near-fatal illness into…
Read More Pharmacology of antiretroviral drugs
Posted by Pharmacology Mentor January 6, 2025
Antimicrobial stewardship
Posted inAntimicrobial Pharmacology

Antimicrobial stewardship

Antimicrobial stewardship is the coordinated set of actions that ensures the optimal selection, dosing, route, and duration of antimicrobial therapy to improve clinical outcomes while minimizing toxicity, resistance, and costs.…
Read More Antimicrobial stewardship
Posted by Pharmacology Mentor March 23, 2024
Antiretroviral drugs
Posted inAntimicrobial Pharmacology

Antiretroviral Drugs

Introduction Antiretroviral drugs have revolutionized the treatment of HIV, turning what was once a fatal diagnosis into a manageable chronic condition. These medications, central to HIV treatment and management, work…
Read More Antiretroviral Drugs
Posted by Dr. Ambadasu Bharatha January 15, 2024
Albendazole
Posted inAntimicrobial Pharmacology

Pharmacology of Albendazole

Albendazole is a broad-spectrum benzimidazole anthelmintic that disrupts parasite microtubules and energy metabolism, leading to ovicidal, larvicidal, and vermicidal effects across key helminth infections. Clinically, it is FDA-approved for parenchymal…
Read More Pharmacology of Albendazole
Posted by Pharmacology Mentor December 18, 2023
Clindamycin
Posted inAntimicrobial Pharmacology

Pharmacology of Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic that exerts its antimicrobial action by binding to the 23S rRNA of the 50S ribosomal subunit, thereby inhibiting bacterial protein synthesis through blockage of…
Read More Pharmacology of Clindamycin
Posted by Pharmacology Mentor December 18, 2023
Linezolid
Posted inAntimicrobial Pharmacology

Pharmacology of Linezolid

Linezolid is a synthetic oxazolidinone antibiotic indicated for serious Gram-positive bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), and penicillin-resistant Streptococcus pneumoniae. It is…
Read More Pharmacology of Linezolid
Posted by Pharmacology Mentor December 18, 2023

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