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FDCs
Posted inGeneral Pharmacology

Pharmacotherapy: The Drug Dosage and Fixed Dose Combinations (FDCs)

Introduction Are you looking to demystify the complex world of pharmacotherapy? Whether you're a healthcare provider, a patient, or someone interested in medical science, understanding the nuances of drug dosage…
Read More Pharmacotherapy: The Drug Dosage and Fixed Dose Combinations (FDCs)
Posted by Pharmacology Mentor August 31, 2023
Chelating agents
Posted inmiscellaneous Pharmacology

Chelating Agents for Heavy Metal Poisoning: What You Need to Know

Introduction Chelating agents are specialized chemical compounds that bind toย metal ions, forming one or more stable complexes in the process. By effectively โ€œgrabbingโ€ metals, these agents can help treatย metal poisoning,…
Read More Chelating Agents for Heavy Metal Poisoning: What You Need to Know
Posted by Pharmacology Mentor August 31, 2023
Carbonic Anhydrase Inhibitors
Posted inCVS Pharmacology

Pharmacology of Carbonic Anhydrase Inhibitors

I. Introduction and Class Overview Carbonic anhydrase inhibitors (CAIs) are a class of drugs that reversibly inhibit the enzyme carbonic anhydrase, thereby interfering with HCOโ‚ƒโป (bicarbonate) reabsorption and decreasing hydrogen…
Read More Pharmacology of Carbonic Anhydrase Inhibitors
Posted by Pharmacology Mentor August 31, 2023
Osmotic Diuretics
Posted inCVS Pharmacology

Pharmacology of Osmotic Diuretics

Mechanism of Action: Osmotic diuretics work by increasing the osmolarity of the filtrate in the renal tubules. The glomerulus filters them but does not reabsorb them, creating an osmotic gradient…
Read More Pharmacology of Osmotic Diuretics
Posted by Pharmacology Mentor August 31, 2023
Potassium-sparing diuretics
Posted inCVS Pharmacology

Pharmacology of Potassium-Sparing Diuretics

Potassium-sparing diuretics are a class of diuretic medications that increase diuresis (urine production) while conserving potassium, contrasting with thiazide and loop diuretics that promote potassium loss. They are used primarily…
Read More Pharmacology of Potassium-Sparing Diuretics
Posted by Pharmacology Mentor August 31, 2023
thiazide diuretics
Posted inCVS Pharmacology

Pharmacology of Thiazide Diuretics

Thiazide diuretics are cornerstone antihypertensive and mildโ€‘toโ€‘moderate diuretic agents that inhibit the thiazideโ€‘sensitive Naโ€‘Cl cotransporter in the distal convoluted tubule, lowering blood pressure and mobilizing edema with characteristic effects on…
Read More Pharmacology of Thiazide Diuretics
Posted by Pharmacology Mentor August 31, 2023
loop diuretics
Posted inCVS Pharmacology

Pharmacology of Loop Diuretics

Introduction Loop diuretics are a cornerstone of therapy in conditions where rapid and potent diuresis (urine output) is required. By inhibiting sodium and chloride reabsorption in the thick ascending limb…
Read More Pharmacology of Loop Diuretics
Posted by Pharmacology Mentor August 31, 2023
first-order vs zero-order kinetics
Posted inGeneral Pharmacology

First-Order vs. Zero-Order Kinetics: What You Need to Know

Zero-Order Kinetics Definition: In zero-order kinetics, the rate of drug elimination is constant and does not depend on the drug concentration. This is often seen with drugs that saturate the…
Read More First-Order vs. Zero-Order Kinetics: What You Need to Know
Posted by Pharmacology Mentor August 31, 2023
prolongation of drug action
Posted inGeneral Pharmacology

Prolongation of Drug Action: A Complete Overview

Extending the duration of a drug action can offer several advantages, such as enhanced patient compliance, reduced frequency of dosing, and minimized side effects. However, it's crucial to understand that…
Read More Prolongation of Drug Action: A Complete Overview
Posted by Pharmacology Mentor August 31, 2023
kinetics of elimination
Posted inGeneral Pharmacology

Kinetics of Elimination: A Complete Overview of Mechanisms and Implications

Understanding the kinetics of how a drug is removed from the body is foundational for creating and adjusting rational dosage plans tailored to individual patient needs. Three key pharmacokinetic parameters…
Read More Kinetics of Elimination: A Complete Overview of Mechanisms and Implications
Posted by Pharmacology Mentor August 30, 2023

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