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irritable bowel syndrome
Posted inGI Pharmacology

Irritable Bowel Syndrome (IBS)

Introduction Irritable Bowel Syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by abdominal pain and altered bowel habits in the absence of any identifiable structural or biochemical abnormalities. IBS…
Read More Irritable Bowel Syndrome (IBS)
Posted by Pharmacology Mentor November 21, 2023
GERD
Posted inGI Pharmacology

Gastroesophageal Reflux Disease (GERD)

I. Introduction Gastroesophageal reflux disease (GERD) is a chronic disorder characterized by the reflux of gastric contents into the esophagus, which leads to troublesome symptoms, mucosal injury, and, in some cases,…
Read More Gastroesophageal Reflux Disease (GERD)
Posted by Pharmacology Mentor November 21, 2023
peptic ulcer disease - PUD
Posted inGI Pharmacology

Peptic Ulcer Disease (PUD) – A brief note

Introduction Peptic Ulcer Disease (PUD) is a gastrointestinal disorder characterized by sores or lesions in the lining of the stomach or duodenum. It is a significant health concern worldwide, affecting…
Read More Peptic Ulcer Disease (PUD) – A brief note
Posted by Pharmacology Mentor November 21, 2023
helicobacter_pylori
Posted inGI Pharmacology

Helicobacter pylori Infection and Treatment

Introduction Helicobacter pylori (H. pylori) is a spiral-shaped, gram-negative bacterium that colonizes the human stomach and duodenum. First identified in the early 1980s, this organism quickly garnered attention due to its…
Read More Helicobacter pylori Infection and Treatment
Posted by Pharmacology Mentor November 21, 2023
ZE syndrome
Posted inGI Pharmacology

Zollinger-Ellison Syndrome (ZES)

I. Definition, Historical Perspective & Epidemiology Zollinger–Ellison Syndrome (ZES) is a rare disorder characterized by gastrin-secreting tumors (“gastrinomas”) of the pancreas or duodenum. These tumors lead to excessive gastric acid secretion,…
Read More Zollinger-Ellison Syndrome (ZES)
Posted by Pharmacology Mentor November 21, 2023
pharmacovigilence
Posted inClinical Pharmacology Pharmacology

Pharmacovigilance

1 · Introduction Pharmacovigilance (PV) is the “science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine-related problem” (WHO). In an era of…
Read More Pharmacovigilance
Posted by Pharmacology Mentor November 19, 2023
oxytocin-word-love-hormone-medical-concept-scaled
Posted inmiscellaneous Pharmacology

Pharmacology of Oxytocin

Oxytocin, a neuropeptide hormone produced by the hypothalamus and secreted by the posterior pituitary gland, has garnered significant attention in recent years due to its diverse physiological and psychological effects.…
Read More Pharmacology of Oxytocin
Posted by Pharmacology Mentor November 17, 2023
tocolytic agents
Posted inmiscellaneous Pharmacology

Pharmacology of Tocolytic Agents

I. Introduction Tocolytic agents are medications used to inhibit uterine contractions and suppress premature labor, thereby prolonging pregnancy long enough for vital fetal benefits—particularly the administration of antenatal corticosteroids and safe…
Read More Pharmacology of Tocolytic Agents
Posted by Pharmacology Mentor November 17, 2023
thyroid and antithyroid drugs
Posted inEndocrine Pharmacology

Pharmacology of thyroid and antithyroid drugs – an Overview

Physiology of Thyroid Hormones Thyroid gland secretes T4 (thyroxine) and T3 (triiodothyronine); T3 is more potent, T4 is a prohormone converted peripherally to T3. Regulation: Hypothalamic-pituitary-thyroid axis (TRH → TSH → thyroid…
Read More Pharmacology of thyroid and antithyroid drugs – an Overview
Posted by Pharmacology Mentor November 11, 2023
prostaglandin analogues
Posted inmiscellaneous Pharmacology

Pharmacology of Prostaglandin Analogues

I. Introduction Prostaglandins are autacoids derived from arachidonic acid via the cyclooxygenase pathway and modulate numerous physiological processes—vascular tone, inflammation, gastric cytoprotection, uterine contraction, and intraocular pressure. Prostaglandin analogues are…
Read More Pharmacology of Prostaglandin Analogues
Posted by Dr. Ambadasu Bharatha November 11, 2023

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