Metronidazole: an antibiotic and antiprotozoal medication
Introduction Metronidazole is a widely used antimicrobial agent recognized for its efficacy against anaerobic bacteria and protozoa. Derived from nitroimidazole, metronidazole disrupts the DNA of target microorganisms, halting their replication. It was first…
Clindamycin: a lincosamide antibiotic
Clindamycin is a lincosamide antibiotic widely used for its excellent activity against many Gram-positive cocci and anaerobes. It is valued for oral and parenteral versatility, tissue penetration (including bone), and its…
Pharmacology of Linezolid
Introduction Among the modern arsenal of antibiotics, linezolid occupies a key position in the management of drug-resistant Gram-positive infections. Approved by the U.S. FDA in 2000, linezolid heralded the first-in-class oxazolidinone family of antibacterials,…
Pharmacology of Vancomycin
Vancomycin is a glycopeptide antibiotic principally used in the treatment of severe infections caused by Gram-positive bacteria, particularly those resistant to beta-lactams such as MRSA (methicillin-resistant Staphylococcus aureus), penicillin-resistant streptococci,…
Pharmacology of Co-trimoxazole
Introduction Co-trimoxazole—a combination of sulfamethoxazole and trimethoprim—has been a cornerstone antibacterial agent for decades. The synergy between these two drugs proves highly effective against a broad range of Gram-positive and Gram-negative microorganisms. First introduced in the 1960s,…
Pharmacology of Aminoglycoside antibiotics
INTRODUCTION Aminoglycoside antibiotics are a class of potent, broad-spectrum bactericidal agents that have played a critical role in the management of serious bacterial infections for decades. First derived from microbial…
Pharmacology of Fluoroquinolones
Fluoroquinolones are one of the most significant classes of broad-spectrum antimicrobial agents used in modern medicine. With their ability to target both Gram-positive and Gram-negative bacteria, these agents are frequently employed in various clinical…
Pharmacology of Macrolides
Macrolides are a group of antibiotics characterized by a macrocyclic lactone ring attached to various amino or neutral sugars. They are widely used in clinical medicine, particularly against respiratory pathogens…
Pharmacology of Tetracyclines
Tetracyclines are a class of broad-spectrum antibiotics that are effective against a wide variety of bacteria. They are commonly used to treat infections of the respiratory tract, skin, and urinary…
An In-depth Look into Medical Prescriptions
Introduction Medical prescriptions are a cornerstone in the healthcare sector, forming a vital communication bridge between physicians and pharmacists and ensuring that patients receive the correct medication in a timely…