Neuropharmacology

Pharmacology of Barbiturates

Introduction Barbiturates are among the earliest classes of sedative-hypnotic drugs discovered and used clinically. Derived from barbituric acid, these compounds exert a depressant influence on the central nervous system (CNS),...

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Neuropharmacology

Pharmacology of Selective serotonin reuptake inhibitors (SSRIs)

Introduction Selective Serotonin Reuptake Inhibitors (SSRIs) revolutionized the treatment of depression and related affective disorders in the late 20th century. Since their introduction, SSRIs have become the first-line pharmacological...

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Neuropharmacology

Pharmacology of Paracetamol/Acetaminophen

Introduction Paracetamol—known as acetaminophen in some regions—is one of the most widely used analgesics and antipyretics. Celebrated for its efficacy and relatively favorable safety profile compared to...

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Neuropharmacology

Aspirin: A Comprehensive Pharmacological Overview

Aspirin, scientifically known as acetylsalicylic acid (ASA), is a cornerstone in the world of nonsteroidal anti-inflammatory drugs (NSAIDs). With its multifaceted roles as an analgesic, antipyretic, and...

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Neuropharmacology

Understanding Cyclooxygenase (COX) Enzymes

Cyclooxygenase (COX), which is also called prostaglandin-endoperoxide synthase (PTGS), is an enzyme that converts arachidonic acid into prostanoids like thromboxane and prostaglandins like prostacyclin. This...

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Neuropharmacology

Pharmacology of Benzodiazepines

Introduction Benzodiazepines are a cornerstone of modern pharmacotherapy for anxiety, insomnia, seizure disorders, muscle spasms, and other related conditions. By enhancing the effects of the primary inhibitory neurotransmitter in...

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Pharmacology

Pharmacology of Antitussives

Introduction A cough is one of the most common clinical symptoms that prompts patients to seek medical care. Although it serves a critical protective role in clearing...

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GI

Pharmacology of antiemetic drugs

Introduction Nausea and vomiting are protective reflexes designed to prevent the ingestion or continued digestion of harmful toxins. However, when severe, they can significantly deteriorate...

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GI

Pharmacology of Mucosal Protective Agents

Introduction Peptic ulcer disease, gastritis, gastroesophageal reflux disease (GERD), and other erosive conditions of the gastrointestinal (GI) tract rank among the most common and debilitating...

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GI

Pharmacology of Antacids

Introduction Antacids represent one of the oldest and most commonly used groups of medications for gastrointestinal acidity-related disorders. By chemically neutralizing excessive gastric acid, antacids rapidly relieve...

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