Antimicrobial Chemotherapy – Antibacterials

Linezolid is best used for:

This bacterial protein synthesis inhibitor is used for management of abdominal abcess caused by Bacteroides fragilis. Antibiotic associated colitis commonly occurs with use of this drug. Which of the following drug is being described?

Empirical treatment for meningococcal meningitis is:

A 26 year old patient presents with suspected pneumococcal meningitis. CSF culture is sent for antibiotic sensitivity. Which empirical antibiotic should be given till culture sensitivity result come?

Treatment of choice for chancroid is:

A patient diagnosed as having ventilator associated pneumonia, is on treatment with ceftriaxone and amikacin. Culture and sensitivity turned out to be positive for ESBL producing Klebsiella infection. The most appropriate next action should be:

Drug of choice for sore throat caused by Group A beta hemolytic streptococcus is:

In the given below figure at which site does penicillinase work?

Erythromycin is drug of choice for treatment of diarrhea in children caused by:

Single dose aminoglycoside administration is more preferable than 8 hourly dose because of:

The persistent suppression of bacterial growth that may occur after limited exposure to some antimicrobial drug is called:

Mechanism of action of fluoroquinolones is:

Ciprofloxacin should not be given to an asthmatic using theophylline because:

A girl on sulphonamides developed abdominal pain and presented to emergency with seizure. What is the probable cause?

Drug of choice for prophylaxis of Pneumocystis jiroveci pneumonia in immunocompromised patients is:

Which one of the following drugs is an antipseudomonal penicillin?

Which of the following aminoglycosides has highest nephrotoxicity?

Redman syndrome is due to:

A post operative patient developed septicemia and was empirically started on combination chemotherapy by a new resident doctor. However, when the patient did not respond even after 10 days of antibiotics treatment, the review of the charts was done. It was found that the resident doctor had started the combination of antibiotics which was mutually antagonistic in action. Which of the following is the most likely combination that was given?

Which of the following drugs is used in the treatment of acute bacterial meningitis?

A 21-year-old marathon runner reports to the clinic with acute Achilles tendon rupture. The nurse noted that the patient recently took an antibiotic for community-acquired pneumonia. Which antibiotic may have contributed to tendon rupture?

Drug of choice for antibiotic associated pseudomembranous colitis is:

After 5 days of clindamycin treatment for a skin infection, a patient develops diarrhea (10 watery stools/day), severe abdominal pain, and fever. Which of the following organisms would you be concerned about as the causative pathogen of diarrhea?

A 68-year-old man presents from a nursing home with fever, increased urinary frequency and urgency, and mental status changes. He has a penicillin allergy of anaphylaxis. Which of the following β-lactams is the most appropriate choice for gram-negative coverage of this patient’s urinary tract infection?

A child was admitted to the hospital with H. influenza meningitis. Cefotaxime is preferred over ampicillin because:

A 23-year-old man was started on standard four-drug antimycobacterial therapy for treatment of active TB. He has epilepsy, which is controlled with carbamazepine. He has had no seizures in 5 years; however, upon return to clinic at 1 month, he reports having two seizures since his last visit. Which drug may be the reason his carbamazepine is less effective?

Drug of choice for prophylaxis of meningococcal meningitis is:

A potent inhibitor of beta-lactamase is:

Which of the following should be monitored if linezolid is given for more than 14 days?

Mechanism of action of vancomycin is:

Drug of choice for acute meningococcal pyogenic meningitis is:

Which of the following antibiotic acts by inhibiting cell wall synthesis?

Which of the following drugs act by inhibiting bacterial protein synthesis?

Which of the following adverse effects is often employed as a therapeutic use for erythromycin?