Antimicrobial chemotherapy - Quizzes| Pharmacology Mentor

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ANTIVIRAL AND ANTIFUNGAL DRUGS

Quiz on Antimicrobial Chemotherapy - Antiviral and antifungal drugs:

Amphotericin B toxicity can be reduced by?

Incorporating it in liposomal complex

Combining with fluconazole

Combining with flucytosine

Injecting the drug with dextrose

None

Which drug would treat both dermatophytosis and candidal infections?

Tolnaftate

Ketoconazole

Nystatin

Griseofulvin

None

Drug of choice in herpes simplex encephalitis is:

Acyclovir

Amantadine

Vidarabine

Interferon

None

A diabetic patient presents with fungal infection of sinuses and peri-orbital region with significant visual impairment. The best drug for treatment of this patient is:

Itraconazole

Broad spectrum antibiotics

Ketoconazole

Amphotericin B

None

A person is being treated for Human Immunodeficiency Virus-1. He developed hypertriglyceridemia and hypercholesterolemia. Most likely drug implicated for these adverse effects is:

Ritonavir

Efavirenz

Didanosine

Raltegravir

None

Pancreatitis is a common complication of which one of the following:

Stavudine

Zidovudine

Didanosine

Zalcitabine

None

Drug of choice for chronic hepatitis –B is:

Lamivudine

Zidovudine

Ribavirin

IFN-alpha

None

Which of the following anti-metabolites act as an antifungal agent?

5-Flucytosine (5 FC)

Chlorambucil

Decarbazine

Paclitaxel

None

Drug of choice for acyclovir resistant herpes is:

Foscarnet

Cidofovir

Gancyclovir

Valacyclovir

None

10.

Which of the following has poorest oral bioavailability?

Amantadine

Zanamivir

Rimantidine

Oseltamivir

None

11.

Drug of choice for herpes simplex keratitis is:

Acyclovir

Ganciclovir

Interferon

Amantadine

None

12.

Drug causing maximum peripheral neuropathy is:

Zidovudine

Lamivudine

Stavudine

Didanosine

None

13.

Liposomal amphotericin B has the following advantage over conventional amphotericin B:

Once a week administration

Lesser nephrotoxicity

Lesser cost

Absence of infusional toxicity

None

14.

The drug used to treat acyclovir resistant Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV) infection is:

Ganciclovir

Valacyclovir

Foscarnet

Abacavir

None

15.

Following drugs act against HIV-2 except:

Tenofovir

Ritonavir

Zalcitabine

Efavirenz

None

16.

Drug of choice for herpes simplex virus infection is:

Indinavir

Ribavarin

Acyclovir

Zidovudine

None

17.

The antimicrobial agent which inhibits the ergosterol biosynthesis is:

5-Flucytosine

Griseofulvin

Amphotericin B

Fluconazole

None

18.

Which of the following drugs is used to prevent HIV transmission from an HIV positive pregnant mother to child? (AIIMS Nov. 2011)

Lamivudine

Nevirapine

Stavudine

Didanosine

None

19.

The minimum period required for post-exposure chemoprophylaxis for HIV is:

8 weeks

12 weeks

6 weeks

4 weeks

None

20.

Enfuvirtide belongs to the class of:

Gp 120 inhibitors

Nucleotide reverse transcriptase inhibitors

Fusion inhibitors

Protease inhibitors

None

21.

Treatment of choice for coccidiodomycosis is:

Amphotericin

Fluconazole

Griseofulvin

Flucytosine

None

22.

Mechanism of action of oseltamivir is:

Block DNA dependent RNA polymerase

Blocks M2 protein

Apoptosis of respiratory epithelial cells

Neuraminidase inhibitor

None

23.

Which of the following is oral drug for treatment of hepatitis C?

Ribamivir

Ledipasvir

Peg-interferon

Lamivudine

None

24.

All of the following are common adverse effects of HAART therapy except:

Increased cholesterol

Optic neuritis

Steatosis

Lipodytrophy

None

25.

Mechanism of action of terbinafine is?

Inhition of microtubule formation

Binds to ergosterol

Inhibition of ergosterol synthesis

Prevents formation of purine

None

26.

Mechanism of action of protease inhibitors is:

Inhibits proviral RNA synthesis

Prevents translation of viral RNA

Causes apoptosis of the affected cells

Prevents maturation of new viral particles

None

27.

Which of the following is most common side effect of zidovudine?

Peripheral neuropathy

Lactic acidosis

Anemia

None

28.

Drugs that can be used to treat candida infection are all EXCEPT:

Nystatin

Amphotericin

Griseofulvin

Ketoconazole

None

1 out of 28

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antiviral Drugs & Antifungal Drugs and are not a comprehensive assessment of the subject.

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ANTIMALARIAL DRUGS

Quiz on Antimicrobial Chemotherapy - Antimalarial Drugs:

Tissue schizontocide which prevents relapse of vivax malaria is:

Chloroquine

Pyrimethamine

Quinine

Primaquine

None

Which one of the following antimalarial drugs is safe for use in pregnancy?

Tetracycline

Atovaquone

Proguanil

Primaquine

None

Which of the following antimalarial drugs is a slow acting schizonticide?

Mefloquine

Quinine

Artemether

Pyrimethamine

None

Drug of choice in a patient with severe complicated falciparum malaria is:

Artesunate

Quinine

Chloroquine

Artemether

None

Radical cure is required for malaria caused by:

P. falciparum and P. vivax

P. falciparum and P. malariae

P. vivax and P. malariae

P. vivax and P. ovale

None

Which antimalarial drug is known to cause neuropsychiatric adverse reaction?

Artimisnin

Artesunate

Mefloquine

Quinine

None

Radical cure of Plasmodium vivax is by:

Artesunate

Chloroquine

Tetracycline

Primaquine

None

Drug of choice for chloroquine resistant malaria in pregnancy is:

Artemisinin

Mefloquine

Sulphadoxine + pyrimethamine

Quinine

None

Which of the following can cause hypoglycemia in a patient of severe cerebral malaria on treatment?

Quinine

Chloroquine

Halofantrine

Mefloquine

None

10.

Choose the drug whose single oral dose affords clinical cure of uncomplicated malaria caused by chloroquine sensitive/resistant P. falciparum as well as P. vivax:

Proguanil

Artesunate

Mefloquine

Quinine

None

11.

Drug of choice for the treatment of a pregnant woman with P vivax malaria is:

Quinine

Paracetamol

Chloroquine

Artemether

None

12.

Chemoprophylaxis in an Englishman visiting chloroquine and mefloquine resistant malaria region is done with:

Primaquine

Hydroxychloroquine

Doxycycline

Amodiaquine

None

13.

Which of the following drugs can be used for the treatment of chloroquine resistant malaria in children?

Chloroquine

Clindamycin

Tetracycline

Doxycycline

None

14.

The development of resistance to conventional treatment has led WHO to recommend the use of combination therapies containing artemisinin derivative (artemisinin-based combination therapies also known as ACTs). All of the following combination therapies are recommended if such resistance is suspected, except:

Artesunate plus mefloquine

Artesunate plus pyrimethamine-sulfadoxine

Artemether plus lumefantrine

Artesunate plus quinine

None

15.

Chloroquine is given as 600 mg loading dose because:

It is rapidly absorbed

It is rapidly metabolized

It is rapidly eliminated

It has increased tissue binding

None

16.

Drug of choice for treatment of chloroquine resistant falciparum malaria is:

Quinine

Chloroquine

Pyrimethamine

Primaquine

None

17.

Absorption of which of the following anti-malarial drug increases with food intake?

Lumefantrine

Chloroquine

Amodiaquine

Mefloquine

None

18.

Drug of choice for treatment of malaria due to P. vivax in a 25 year old pregnant female is:

Chloroquine

Sulfadoxine-pyrimethamine

Quinine

Primaquine

None

19.

First line drug for falciparum malaria in pregnancy is:

Chloroquine

Primaquine

Tetracycline

Quinine

None

20.

Which one of the following drug may be used for prevention of relapse of P. vivax infection:

Primaquine

Atovaquone

Tetracycline

Chloroquine

None

1 out of 20

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antimalarial Drugs and are not a comprehensive assessment of the subject.

Time's up

ANTIPROTOZOAL AND ANTIHELMINTHIC DRUGS

Quiz on Antimicrobial Chemotherapy: Antiprotozoal and antihelminthic drugs:

Albendazole is effective against all of the following except:

Pinworm

Hookworm

Tapeworm

Roundworm

None

The drug of choice for schistosomiasis is:

Triclabendazole

Albendazole

Praziquantel

Metronidazole

None

A female presented with frothy, greenish vaginal discharge with a musty smell. On examination ‘strawberry vagina’ was noted. A diagnosis of trichomonas vaginalis was made. Drug of choice is:

Fluconazole

Tetracycline

Metronidazole

Erythromycin

None

Scabies can be effectively treated systemically by:

Ivermectin

Psoralens

Permethrin

Contrimoxazole

None

Disulfiram like interaction with alcohol is seen with all of the following drugs EXCEPT:

Cefoperazone

Metronidazole

Satranidazole

Griseofulvin

None

Drug of choice for kala-azar is:

Sodium stibogluconate

Amphotericin B

Pentamidine

Penicillin

None

Drug commonly used in the treatment of echinococosis is:

Metronidazole

Ivermectin

Albendazole

Pyrental prermeated

None

Amphotericin B produce antifungal action by acting on:

Ribosome

Nucleic acid

Cell wall

Cell membrane

None

Drug of choice for neurocysticercosis is:

Levamisole

Piperazine

Albendazole

Praziquantel

None

10.

Which of the following drug causes flaccid paralysis of ascaris?

Piperazine

Pyrantel pamoate

Ivermectin

Albendazole

None

11.

Metronidazole is effective in all of the following conditions except:

Neurocysticercosis

Amebic liver abscess

Pseudomembranous colitis

Giardiasis

None

12.

All of these are used in the treatment of visceral leishmaniasis except:

Miltefosine

Hydroxychloroquine

Sitamaquine

Paromomycin

None

13.

Drug of choice for medical treatment of hydatid cyst of liver is:

Praziquantel

Albendazole

Thiabendazole

Ivermectin

None

14.

Ivermectin is used for the treatment of:

Teniasis

Filariasis

Ascariasis

Hookworm infestation

None

15.

DEC (Di-ethyl-carbamazine) is used for the treatment of:

Dracunculiasis

Taeniasis

Filariasis

Schistosomiasis

None

16.

Which of the following is not used as treatment for lymphatic filariasis?

Ivermectin

Diethyl carbamazine

Praziquantel

Albendazole

None

17.

Drug of choice for hookworm infestation is:

Albendazole

Mebendazole

Piperazine citrate

Bephenium hydroxynaphthoate

None

18.

Round worm infection is best treated with:

Metronidazole

Pyrantel pamoate

Mebendazole

Albendazol

None

19.

Bull’s eye retinopathy is seen in:

Ethambutol

Steroids

Methanol

Chloroquine

None

1 out of 19

Feel free to ask questions and provide any feedback/suggestions by filling in the comment box below.

Thanks for completing the Quiz!

Please note: These MCQs are intended as a general overview of Antimicrobial Chemotherapy - Antiprotozoal & antihelminthic drugs and are not a comprehensive assessment of the subject.

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How to cite this page - Vancouver Style

Mentor, Pharmacology. PRACTICE QUIZZES on antimicrobial chemotherapy. Pharmacology Mentor. Available from: https://pharmacologymentor.com/practice-quizzes-on-antimicrobial-chemotherapy/. Accessed on February 19, 2026 at 19:18.

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