Antiplatelet drugs, Anticoagulants and Fibrinolytics

Pharmacology Mentor

Antiplatelet Drugs Antiplatelet drugs are a class of medications that prevent blood clots from forming. They work by stopping your platelets from sticking together. Antiplatelet drugs are used to avoid blood clots, which can cause heart attacks and strokes. • The main component of arterial thrombi is platelets, and the release of chemicals like ADP, TXA2, and … Read more

Sildenafil: Its Use as a PDE5 Inhibitor for Erectile Dysfunction

sildenafil

Phosphodiesterase type 5 (PDE5) inhibitors are first‑line oral agents for erectile dysfunction that augment the endogenous nitric oxide–cGMP pathway in the corpus cavernosum to facilitate erection with sexual stimulation, and the class includes sildenafil, vardenafil, tadalafil, and avanafil. Standard pharmacology texts detail shared mechanisms with clinically important differences in onset, duration, food effects, selectivity, and … Read more