Antiarrhythmic drugs: Mexiletine (Class 1B)
Mexiletine is an oral Class IB antiarrhythmic and sodium channel blocker structurally related to lidocaine, used primarily for ventricular arrhythmias and selected channelopathies such as LQT3 where late sodium current inhibition is desired.Its key antiarrhythmic actions are fast-on/fast-off block of fast Na+ channels with preference for inactivated channels in ischemic tissue, leading to rate‑dependent suppression … Read more