Pharmacology of Opioid Analgesics

Opioid analgesics

Introduction Opioid analgesics comprise a diverse class of drugs used primarily for pain management. Derived from natural sources such as the opium poppy or synthesized in laboratories, these agents have been used for centuries for their potent analgesic and sedative properties. Opioids remain the most effective agents for controlling intense and certain chronic pain syndromes, … Read more

Androgens and Antiandrogens

androgens and antiandrogens

Androgens are steroid hormones that promote the development and maintenance of male sex characteristics. The principal naturally occurring androgens in humans are testosterone and dihydrotestosterone (DHT), both synthesized mainly in the testes and, to a lesser extent, the adrenal cortex. Androgens bind to intracellular androgen receptors (AR), acting as transcription factors to regulate gene expression … Read more