Drugs Used for Peptic Ulcer Disease (PUD)
Overview Peptic ulcer disease (PUD) encompasses ulceration of the gastric or duodenal mucosa due to an imbalance between aggressive factors (gastric acid, pepsin, Helicobacter pylori, bile, and nonsteroidal anti-inflammatory drugs [NSAIDs]) and mucosal defenses (mucus-bicarbonate barrier, prostaglandins, mucosal blood flow, epithelial restitution). Pharmacologic therapy aims to relieve symptoms, promote healing, prevent complications (bleeding, perforation, obstruction), … Read more