Histamine H2 receptor antagonists are competitive blockers of gastric parietal-cell H2 receptors that suppress basal and stimulated acid secretion and are used for GERD, peptic ulcer disease, hypersecretory states, and selected prophylaxis indications, with famotidine preferred clinically because of potency and safety while ranitidine has been withdrawn for NDMA contamination concerns. The class reduces nocturnal … Read more
Methanol (methyl alcohol, wood alcohol) is a simple aliphatic alcohol with significant toxicological importance. It is colorless, volatile, and commonly used as a solvent, antifreeze, fuel, and in industrial chemical processes. Accidental or intentional ingestion of methanol, as well as inhalation or dermal exposure, can result in severe toxicity and death. The cardinal feature of … Read more
Introduction Have you ever wondered about the drugs that counteract the effects of the sympathetic nervous system? Sympatholytics, also known as adrenergic antagonists, are one such class of drugs. This article will dive into the classification, pharmacological actions, clinical uses, adverse effects, and contraindications of different types of sympatholytic drugs. So, let’s get started! Sympatholytics … Read more