Diarrhea

Pharmacology of H2 Receptor Antagonists

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H2 Receptor Antagonists

Histamine H2 receptor antagonists are competitive blockers of gastric parietal-cell H2 receptors that suppress basal and stimulated acid secretion and are used for GERD, peptic ulcer disease, hypersecretory states, and selected prophylaxis indications, with famotidine preferred clinically because of potency and safety while ranitidine has been withdrawn for NDMA contamination concerns. The class reduces nocturnal … Read more

Parasympathomimetics/Cholinergic agonists

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parasympathomimetics

Introduction Parasympathomimetics — also referred to as cholinergic agonists or muscarinic agonists—are a class of medications that enhance or mimic the actions of the parasympathetic nervous system (PNS). The PNS is one subdivision of the autonomic nervous system, often described as the “rest and digest” branch. Through stimulation of acetylcholine (ACh) receptors, parasympathomimetics elicit various physiological responses such … Read more