Understanding Alteplase: The Tissue Plasminogen Activator You Need to Know
Introduction Alteplase (also referred to as recombinant tissue plasminogen activator or rt-PA) is a cornerstone of thrombolytic therapy, widely used to treat acute ischemic stroke, acute myocardial infarction, and other thromboembolic conditions. As a bioengineered form of tissue plasminogen activator (tPA), alteplase exerts its therapeutic effect by converting plasminogen to plasmin, thereby dissolving clots that obstruct blood flow … Read more