Aspirin, scientifically known as acetylsalicylic acid (ASA), is a cornerstone in the world of nonsteroidal anti-inflammatory drugs (NSAIDs). With its multifaceted roles as an analgesic, antipyretic, and anti-inflammatory agent, aspirin has secured its position as one of the most frequently administered medications worldwide. Mechanism of Action At the heart of aspirin’s mechanism is its ability to irreversibly … Read more
Understanding NSAIDs: What are they? Non-Steroidal Anti-Inflammatory Drugs, commonly known as NSAIDs, are a class of drugs primarily used for their analgesic (pain-relieving), antipyretic (fever-reducing), and, as their name suggests, anti-inflammatory effects. They’re a staple in medicine cabinets worldwide and for a good reason. But to truly appreciate these drugs, we need to delve deeper … Read more
Non-steroidal anti-inflammatory drugs (NSAIDs) are cornerstone analgesic, antipyretic, and anti-inflammatory agents whose primary mechanism is inhibition of cyclooxygenase (COX) enzymes to reduce prostaglandin and thromboxane synthesis. A complete pharmacology chapter should cover COX biology, detailed classification, pharmacokinetics/dynamics, therapeutic uses, adverse effects, drug interactions, special populations, and evidence-based risk mitigation strategies from standard pharmacology texts and … Read more