Introduction Paracetamolโknown as acetaminophen in some regionsโis one of the most widely used analgesics and antipyretics. Celebrated for its efficacy and relatively favorable safety profile compared to nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids, paracetamol has become a mainstay of pain management protocols worldwide (Goodman & Gilman, 2018). It is commonly prescribed or bought over-the-counter for mild to … Read more
Understanding NSAIDs: What are they? Non-Steroidal Anti-Inflammatory Drugs, commonly known as NSAIDs, are a class of drugs primarily used for their analgesic (pain-relieving), antipyretic (fever-reducing), and, as their name suggests, anti-inflammatory effects. They’re a staple in medicine cabinets worldwide and for a good reason. But to truly appreciate these drugs, we need to delve deeper … Read more
Non-steroidal anti-inflammatory drugs (NSAIDs) are cornerstone analgesic, antipyretic, and anti-inflammatory agents whose primary mechanism is inhibition of cyclooxygenase (COX) enzymes to reduce prostaglandin and thromboxane synthesis. A complete pharmacology chapter should cover COX biology, detailed classification, pharmacokinetics/dynamics, therapeutic uses, adverse effects, drug interactions, special populations, and evidence-based risk mitigation strategies from standard pharmacology texts and … Read more