Drugs acting on CNS – All CNS topics EXCEPT NSAIDs

All of the following are CNS stimulants except:

A 30-year old epileptic female, Kamla on phenytoin therapy, developed weakness and fatigue. Blood examination revealed Hb = 4.6 gm. MCV = 102 fl and MCH = 40 pg/dl. What is the most probable diagnosis?

Rave drug is?

A 30 year old female, married since one year, presents to the psychiatry clinic with hyperactivity since 2 weeks. A diagnosis of mania is made. She had 3 prior episodes of mania in last 5 years and every time after taking medication she goes to premorbid state. Her urine pregnancy test is positive. Which is the preferred drug for management of this patient?

Drug used in day care anaesthesia is:

Both barbiturates and salicylates are maximally absorbed in stomach because:

A young man is with known heroin addiction is brought in the emergency in unconscious state. On examination, the patient has decreased bowel sounds, depressed respiration and pin point pupil. The treatment of choice for this patient is:

Which one of the following drug is contraindicated in acute myocardial infarction:

Dissociative anesthesia is seen on administration of:

Which of the following does not have analgesic action:

True statement regarding Bupivacaine is:

Methemoglobinemia is caused by:

Which of the following local anaesthetics belongs to the ester group?

Which one of the following drug is used in Alzheimer’s disease?

A patient of schizophrenia was started on haloperidol 5 mg. Next day, he presented with uprolling of eyes. Complete neurological examination revealed no spasticity or any other abnormality. Visual acuity and opthalmoscopic findings are normal. Most likely diagnosis is:

A patient of depression is stabilized on selective serotonin reuptake inhibitor (SSRI). This group of drugs produced withdrawal symptoms when stopped. Which of the following drugs has minimum risk of causing drug discontinuation symptoms?

The effect of thiopentone on the CNS is quickly terminated because of:

A patient presented with vomiting and ataxia. There were oxalate crystals in the urine. The patient was given ethanol and 4 methyl pyrazole for treatment. The likely diagnosis of the patient was?

Opium is a derivative of:

Which of the following drugs is contra-indicated in acute intermittent porphyria?

Nitrous oxide is contraindicated in patients with pneumothorax, pneumopericardium or intestinal obstruction, because it:

Which of the following drug should not be given along with levodopa:

A 65 years old male presented to a hospital with focal seizures. His renal function was normal. Which of the following is the drug of choice for this patient?

A 5 years old child is suffering from cyanotic heart disease. He is planned for corrective surgery. The induction agent of choice would be:

Local anaesthetic used as an antiarrhythmic agent is:

Which of the following abolishes the therapeutic effect of levodopa?

Which of the following is least narcotic opioid?

Neural tube defect is an adverse effect of:

A newborn developed respiratory depression in a postoperative ward. It can result from the use of?

Buprenorphine is:

Which of the following intravenous anesthetic agents is contraindicated in epileptic patients posted for general anesthesia?

Granulocytopenia, gingival hyperplasia and facial hirsutism are all possible side effects of one of the following anticonvulsant drugs?

Which one of the following drugs is used to treat status epilepticus?

In alcohol withdrawal, drug of choice is:

Drug of choice for Trigeminal neuralgia is:

The disulfiram alcohol reaction occurs due to inhibition of which enzyme:

In treatment of Parkinsonism, L-Dopa is combined with carbidopa mainly:

Tolerance develops to all of the following actions of opioids except:

A patient with ruptured spleen is taken for laparotomy. His blood pressure is 80/50 and heart rate is 125/min. Induction agent of choice for this patient is:

From which of the following routes, absorption of local anaesthetic is maximum?

Fetal hydantoin syndrome is seen if following drug is used in pregnancy?

Disulfiram like reaction is not seen with:

Peripheral vasospasm is observed with which of the following anti- Parkinsonian drugs?

Lithium is used in a pregnant woman. Which of the following congenital anomaly occurs in the fetus?

Antidote of methyl alcohol poisoning is:

Which of the following is 100 times more potent than morphine?

An addict presents with increased sweating, lacrimation, diarrhea, yawning and rhinorrhea. These symptoms may occur due to withdrawal of:

The drug of choice to control convulsions in eclampsia is:

In which of the following disorders, administration of barbiturates is contraindicated?

Which among the following drug is contra-indicated in renal failure?

An epileptic adult man is on levetiracetam 1 g twice a day therapy. He is seizure free for 2 years. Now, he started developing irritability, aggression and liability of mood that is affecting his daily life. What should the doctor do?

Drug used for cessation of smoking are all EXCEPT:

Which of the following drugs is used worldwide for the maintenance therapy of opioid dependence?

A patient of Parkinsonism is managed with levodopa. If Vitamin B complex is administered concurrently to the patient:

Inverse agonist of benzodiazepine receptor is:

A patient presented with pain in the right lower quadrant of abdomen. He has history of renal stones in right kidney. He was prescribed an opioid which is agonist at kappa receptors and antagonist at mu receptors. The likely drug given was:

Drug of choice for prophylaxis of mania is:

What is the drug of choice for Obsessive Compulsive Disorder?

A 32-year-old male is a known hypertensive and is being planned for cholecystectomy. Which of the following anaesthetic agents is contraindicated in this person?

A person taking tricyclic antidepressants presents with blurred vision and dry mouth. These adverse effects result due to blockade of:

Which is a treatment of juvenile myoclonic epilepsy in pregnancy?

Which of the following agents enhances the bioavailability of levodopa in patients with Parkinson’s disease:

The specific antidote for benzodiazepine poisoning is:

A female presents with placenta previa with active bleeding and blood pressure of 80/50 mm Hg and pulse rate of 140 bpm. The choice of anaesthesia for emergency cesarean section in this female is?

Drug of choice in drug induced parkinsonism is:

The most important feature of the following opioid analgesic is high oral parenteral activity ratio (1:2):

Profound analgesia is produced by which parenteral anesthetic?

The drug of choice in treatment of infantile spasms is:

Characterstic features of opioid withdrawal is:

Shortest acting benzodiazepine is:

Which of the following has least extrapyramidal side effect:

Which of the following compounds acts as a benzodiazepine antagonist?

A person consumes large quantities of alcohol daily since 20 years. He is physically dependent on alcohol. Drug that should not be given to this person is:

One of the following is not true about melatonin:

A female in labor ward was administered opioid analgesic. Which of the following drugs should be kept ready for emergency?

Opioid analgesic used in treatment of cough is?