Drugs acting on ANS Last updated: 2024/04/15 at 6:45 PM Pharmacology Mentor 148 Views Share 0 Min Read SHARE Welcome to Drugs acting on ANS 1. Drug of choice for mushroom poisoning is: Physostigmine Carbachol Atropine Adrenaline None 2. A 24-years-old farm worker is rushed to a nearby emergency department after an accidental exposure to parathion. Which of the following drugs can be given to increase the activity of his acetyl cholinesterase: Pralidoxime Atropine Dimercaprol Physostigmine None 3. Organophosphates act by inhibiting the enzyme acetylcholinesterase. Which type of enzyme inhibitors are they? Competitive and irreversible Non-competitive and irreversible Uncompetitive and reversible Competitive and reversible None 4. An 80 kg patient is brought in the causality in shock. Dopamine needs to be started at 10 micro/kg/min rate. A 5 mL vial contains 200 mg of dopamine. Two vials are diluted to a solution of 250 mL with the help of normal saline. Calculate drops per minute required to be administered if 1 mL = 16 drops. 32 24 16 8 None 5. The short acting anticholinesterase drug is: Demecarium Dyflos Ectothiophate Edrophonium None 6. Which is the shortest acting mydriatic? Homatropine Cyclopentolate Atropine Tropicamide None 7. Diagnosis of myasthenia gravis is done by using: Succinylcholine Atropine Neostigmine Edrophonium None 8. Neostigmine is not able to cross blood brain barrier because of its: Quarternary structure Secondary structrure Tertiary structure Primary structure None 9. Which of the following drug is a long acting beta-2 agonist? Pirbuterol Albuterol Salmeterol Orciprenaline None 10. Which ONE of the drugs used for atropine toxicity? Flumazenil Physostigmine 2-Pralidoxime Naloxone None 11. Which of the following alpha-blocker drug is used in the treatment of benign hypertrophy of prostate without producing significant hypotension? Dexazosin Terazosin Phentolamine Tamsulosin None 12. A child presented with history of ingestion of some unknown plant and developed mydriasis, tachycardia, dry mouth, warm skin and delirium. Which of the following group of drugs is likely to be responsible for the symptoms of this child? Anticholinergic Benzodiazepine Opioid Sympathomimetic None 13. Antidote for nicotine poisoning is: Neostigmine Atropine sulphate Trimethaphan Phentolamine None 14. All of the following are cardioselective beta blockers EXCEPT: Propranolol Esmolol Atenolol Bisoprolol None 15. The beta blocker having intrinsic sympathomimetic activity is: Propranolol Atenolol Sotalol Pindolol None 16. Drug of choice in treatment of myasthenia gravis is: Neostigmine d-Tubocurarine Gallamine Hexamethonium None 17. Alpha 1a (α1A) adrenergic blocker providing symptomatic relief in BPH is: Prazosin Tamsulosin Tolazoline Doxazosin None 18. A 35-year-old man was found unconscious. Examination revealed bilateral constricted pupils, bradycardia, excessive sweating and secretion. Most likely cause is: Pontine hemorrhage Opium poisoning Organophosphate poisoning Acute alcohol intoxication None 19. Beta blockers are not indicated in: Arrhythmia Chronic CHF Hypertension Acute CHF None 20. Retinoscopy in 5-year-old is best done with: Homatropine Tropicamide Cyclopentolate Atropine None 21. Mechanism of action of pralidoxime is: Inhibition of breakdown of ACh Reactivation of AChE enzyme Stimulation of ACh receptors Blockade of ACh receptors None 22. Which of the following drugs does not cross blood placental barrier? Atropine Glycopyrrolate Physostigmime Hyoscine hydro bromide None 23. A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors and red tears. Plasma cholinesterase level was 30% of normal. Most probable Diagnosis is: Pontine hemorrhage Datura/belladonna poisoning Opioid poisoning Organophosphate poisoning None 24. Atropine is useful in organophosphate poisoning because it: Is a competitive antagonist of acetylcholine Binds with both nicotinic and muscarinic acetylcholine receptors Competes with acetylcholine release Reactivates acetylcholinesterase None 25. Cholinomimetics are useful in all of the following conditions EXCEPT: Myasthenia gravis Partial heart block Post operative atony of bladder Glaucoma None 26. An ultrashort acting β−blocker devoid of partial agonistic or membrane stabilizing action is: Pindolol Esmolol Timolol Atenolol None 27. Ideal drug employed in the preoperative preparation for surgical excision of pheochromocytoma is: Atenolol Reserpine Phenoxybenzamine Clonidine None 28. Major neurotransmitter released at end organ effectors of the sympathic division of the autonomic nervous system is: Adrenaline Dopamine Noradrenaline Acetylcholine None 29. Use of tiotropium is contraindicated in: Urinary retention Bronchial asthma Peptic ulcer disease Hypertension None 30. Pilocarpine reduce the intraocular pressure in persons with closed angle glaucoma by: Relaxing ciliary muscle Increasing aqueous humor outflow Reducing aqueous humor secretion Contracting iris sphincter muscle None 31. A child on β2 agonists for treatment of bronchial asthma may exhibit all of the following features EXCEPT: Hypokalemia Hypoglycemia Tremors Bronchodilation None 32. Treatment of choice for anaphylactic shock is: Adrenaline 0.5 mL of 1:1000 solution by intramuscular route Atropine 3 mg intravenously Adenosine 12 mg intravenously Adrenaline 1 mL of 1:10000 by intravenous route None 33. Beta blockers are indicated for all of the following conditions EXCEPT: Alcohol withdrawal Performance anxiety Hypothyroidism Portal hypertension None 34. Beta blocker having both α and β blocking property is: Sotalol Carvedilol Nadolol Pindolol None 35. A hypertensive patient has heart rate of 50 beats/min and taking tablet atenolol 200 mg/day in divided doses. After anesthesia, heart rate further fell down to 40 beats/min. What will be the appropriate treatment to improve heart rate: IV atropine IV isoprenaline IV adrenaline Dobutamine infusion intravenously None 36. Acetylcholine is not used commercially because: Costly Rapidly destroyed in the body Long duration of action Crosses blood brain barrier None Time's upTime is Up! Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always seek the advice of a healthcare provider with any questions regarding a medical condition. You Might Also Like PHAL6013 practice quiz -2 PHAL6013 practice questions Local Anesthetics Post Lab Quiz – MDSC2203-2023-24 Quiz on Antihyperlipidemics Quiz on Antihypertensives Sign Up For Daily NewsletterBe keep up! Get the latest breaking news delivered straight to your inbox. 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