Parasympatholytics ✓ Passing Score: 50% 📝 Questions: 20 🎓 Practice Quiz Welcome! This is a practice quiz to test your knowledge. Please enter your details below to participate. Your results will be emailed to you upon completion. Your Information Name * Email * Start Quiz → Question 1 of 20 1 Which drug is a competitive antagonist at the neuromuscular junction, often used to induce muscle relaxation during surgery? * Nicotine Pilocarpine Bethanechol Oxybutynin Pancuronium 2 Which of the following is a tertiary amine anticholinergic that readily crosses the blood-brain barrier? * Scopolamine Tiotropium Ipratropium Propantheline Glycopyrrolate 3 Which anticholinergic agent is often used to reduce secretions pre-operatively? * Glycopyrrolate Pindolol Carbachol Varenicline Donepezil 4 A patient presents with SLUDGE syndrome (Salivation, Lacrimation, Urination, Defecation, GI upset, Emesis). Which drug would be the appropriate antidote? * Methacholine Phenylephrine Propranolol Prazosin Atropine 5 A quaternary ammonium compound, such as ipratropium, has the clinical advantage of: * Causing significant peripheral nicotinic effects Crossing the blood-brain barrier easily Being rapidly metabolized by plasma cholinesterases Having potent central nervous system (CNS) effects Being poorly absorbed systemically when inhaled 6 Oxybutynin is commonly prescribed for the management of: * Bronchospasm Peptic ulcer disease Post-operative hypotension Overactive bladder (OAB) Motion sickness 7 Scopolamine is clinically recognized for its effectiveness in preventing: * Nausea and vomiting related to motion sickness Bradycardia during anesthesia Urinary incontinence due to detrusor overactivity Post-operative urinary retention Bronchospasm associated with exercise 8 Overdose with a potent, non-selective anticholinergic drug may present with the mnemonic \\\"Hot as a hare, blind as a bat, dry as a bone, red as a beet, and mad as a hatter.\\\" Which system is responsible for the \\\"mad as a hatter\\\" symptom? * Peripheral alpha-adrenergic blockade Peripheral muscarinic stimulation Central nicotinic stimulation Peripheral nicotinic block Central muscarinic blockade 9 Which statement accurately describes the mechanism of action of non-depolarizing neuromuscular blockers (e.g., rocuronium)? * They inhibit acetylcholinesterase irreversibly. They cause initial depolarization followed by paralysis. They compete with acetylcholine for binding sites on the nicotinic receptor. They are agonists at muscarinic receptors. They prolong the action of acetylcholine at the NMJ. 10 Inhibition of the M2 receptor subtype on the heart leads to which physiological response? * Decreased heart rate (Bradycardia) Increased cardiac contractility Vasoconstriction Decreased conduction velocity Increased heart rate (Tachycardia) 11 Which of the following effects is *least* likely to be observed after administering a therapeutic dose of atropine? * Urinary retention Increased sweating Increased heart rate Dry mouth (xerostomia) Decreased gastric motility 12 Parasympatholytics are generally contraindicated in patients suffering from: * Asthma (acute exacerbation) Narrow-angle glaucoma Post-operative ileus Hypertension Hyperthyroidism 13 Which neurotransmitter is the primary target blocked by parasympatholytic agents? * Dopamine Acetylcholine at muscarinic receptors Acetylcholine at nicotinic receptors Serotonin Norepinephrine at alpha receptors 14 Which condition would necessitate the use of an anti-muscarinic agent to treat excessive salivation (sialorrhea)? * Myasthenia gravis Parkinson\\\'s disease (as an adjunct) Hyperthyroidism Acute heart failure Pheochromocytoma 15 Which drug is classified as an antimuscarinic agent used specifically to treat diarrhea by decreasing intestinal motility? * Propantheline Loperamide Metoclopramide Bethanechol Nicotine 16 Which class of drugs exerts its primary effect by blocking muscarinic acetylcholine receptors? * Beta-blockers Sympathomimetics Alpha-agonists Parasympatholytics Cholinesterase inhibitors 17 The action of which drug is reversed by the administration of physostigmine? * Nicotine Albuterol Scopolamine Norepinephrine Succinylcholine 18 A common side effect associated with the use of therapeutic doses of atropine is: * Cycloplegia (paralysis of accommodation) Bronchoconstriction Increased salivation Miosis (pupil constriction) Bradycardia 19 Which drug is primarily used as an inhaled anticholinergic for the long-term management of COPD? * Tiotropium Succinylcholine Pilocarpine Neostigmine Epinephrine 20 Which type of receptor blockade is responsible for the drying effect (xerostomia) caused by atropine? * Alpha-1 receptors in salivary glands Muscarinic receptors in the cerebral cortex Nicotinic receptors in salivary glands Muscarinic receptors in salivary glands Beta-1 receptors in the CNS ← Previous Next → Submit Quiz ✓