Garlic
Garlic Garlic (Allium sativum) is a culinary herb widely used as a nutraceutical with demonstrated pharmacologic activities. Its therapeutic benefits arise from sulfur‑containing compounds such as alliin, allicin, ajoene, and diallyl…
Ganciclovir
Ganciclovir Ganciclovir is a nucleoside analogue with potent activity against cytomegalovirus (CMV). It is widely used for treatment and prophylaxis of CMV disease in transplant recipients and patients with AIDS-related…
Galcanezumab
Galcanezumab Mechanism of Action Galcanezumab is a humanized monoclonal antibody that selectively binds to the calcitonin gene‑related peptide (CGRP) ligand, preventing its interaction with the CGRP receptor. By neutralizing circulating…
Galantamine
Galantamine Galantamine is a reversible, competitive acetylcholinesterase inhibitor used primarily in the management of mild‑to‑moderate Alzheimer’s disease (AD). It also serves as a positive allosteric modulator of nicotinic acetylcholine receptors…
Gabapentin enacarbil
Gabapentin enacarbil Gabapentin enacarbil is the extended‑release prodrug of gabapentin, designed to improve once‑daily dosing and bioavailability for chronic neuropathic conditions. Mechanism of Action Prodrug conversion: After oral absorption, gabapentin…
Gabapentin
Gabapentin Mechanism of Action Gabapentin is a structural analogue of γ‑aminobutyric acid (GABA) but does not bind GABA receptors. Its main pharmacologic effect is: Binding to the α2δ subunit of…
Fycompa
Fycompa Mechanism of Action Perampanel is a non‑competitive antagonist of the AMPA (α‑amino‑3‑hydroxy‑5‑methyl‑4‑isoxazolepropionic acid) glutamate receptor. By inhibiting excitatory neurotransmission, it reduces neuronal firing and mitigates seizure activity. Unlike phenobarbital…
Furosemide
Furosemide Furosemide is a potent loop diuretic that inhibits the Na⁺‑K⁺‑2Cl⁻ symporter in the thick ascending limb of the loop of Henle, leading to marked natriuresis and diuresis. It is…
Fulvestrant
Fulvestrant Fulvestrant is a selective estrogen receptor degrader (SERD) used primarily for hormone‑receptor‑positive metastatic breast cancer in post‑menopausal women. --- Mechanism of Action Estrogen receptor (ER) antagonism: Binds to the…
Fosfomycin
Fosfomycin Fosfomycin (brand names: Monophas, Fosfomycin Tromethamine, fosfomycin disodium) is a broad‑spectrum, first‑generation phosphonic acid antibiotic. It is available as oral powder for suspensions (often mixed with fruit juice) and…