Glipizide --- Mechanism of Action Glipizide is a second‑generation sulfonylurea that stimulates insulin release from pancreatic β‑cells. Binds the sulfonylurea receptor 1 (SUR1) subunit of the ATP‑sensitive potassium (KATP) channel…
Glimepiride Glimepiride is a second‑generation sulfonylurea used for the management of type 2 diabetes mellitus. It stimulates insulin release from pancreatic β‑cells by binding to the sulfonylurea receptor‑1 (SUR₁) component of…
Gleevec Mechanism of Action Imatinib mesylate (generic name of Gleevec) is a selective ATP‑competitive inhibitor of several tyrosine kinases, most notably the BCR‑ABL oncoprotein, c‑Kit, and platelet‑derived growth factor receptor…
Ginseng Ginseng (Panax spp.) is a popular herbal remedy used traditionally for vitality, cognitive support, and metabolic health. Modern pharmacological studies focus on its active saponins, ginsenosides, and pleiotropic biological…
Ginger Mechanism of Action Anti‑emetic Effects – Ginger antagonizes 5‑HT₃ receptors on the chemoreceptor trigger zone and reduces vagal tone, mitigating nausea and vomiting. Anti‑inflammatory/Prostaglandin Blockage – It inhibits cyclooxygenase‑1…
Giazo Mechanism of Action Giazo is a selective antagonist of the ghrelin (GHS‑R1a) receptor. Competitive inhibition of ghrelin binding prevents downstream activation of the growth hormone secretagogue pathway. Reduction in…
Geodon Mechanism of Action Ziprasidone is a second‑generation antipsychotic. Binding profile: High affinity for dopamine D₂ and serotonin 5‑HT₂A receptors → reduces psychotic symptoms. Partial agonist at 5‑HT₁A receptors →…
Genvoya Genvoya (brand name) = elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide. It is a fixed‑dose combination oral antiretroviral therapy (ART) approved for treatment‑naïve adults with HIV‑1 infection. --- Mechanism of Action Elvitegravir – an…
Gentamicin Topical Gentamicin is an aminoglycoside antibiotic available in ophthalmic (eye drops), otic (ear drops), and dermal (ointment) formulations for superficial bacterial infections. It is formulated for topical use to…