Imuran Mechanism of Action Imuran (azathioprine) is a purine analog prodrug that is intracellularly converted to 6‑mercaptopurine (6‑MP). 6‑MP competes with adenosine and guanine nucleotides for incorporation into DNA and…
Impoyz Impoyz (generic: opiy-inazole, marketed as Impoyz) is a once‑daily oral selective Janus kinase (JAK)1/2 inhibitor used primarily in the management of moderate to severe rheumatoid arthritis (RA) refractory to…
Imiquimod Imiquimod (trade names: Aldara®, Imferon®) is a topical immune‑stimulating agent that acts as a Toll‑Like Receptor 7 (TLR7) agonist, inducing innate and adaptive antiviral and antitumor responses. Mechanism of…
Imipramine Imipramine is a tricyclic antidepressant (TCA) commonly used for depressive disorders and certain neuropathic pains. It has a unique pharmacological profile that makes it useful in both psychiatric and…
Imfinzi Imfinzi (durvalumab) is a human monoclonal IgG1 antibody that selectively blocks the interaction of programmed death‑ligand 1 (PD‑L1) with its receptors PD‑1 and B7‑1, thereby restoring antitumor T‑cell responses.…
Imdur Mechanism of Action Imdur is the brand name for isosorbide mononitrate (IMN), a nitrate vasodilator. Release & Metabolism: Oral IMN is rapidly hydrolyzed to isosorbide dinitrate and subsequently to…
Imdelltra > Disclaimer: > There is currently no publicly available, peer‑reviewed pharmacological data on a drug named Imdelltra in the major drug references, FDA drug database, or peer‑reviewed literature. Consequently,…
Imbruvica Imbruvica (ibrutinib mesylate) is an oral Bruton's tyrosine kinase (BTK) inhibitor approved for several B‑cell malignancies. It targets malignant B‑cells by disrupting B‑cell receptor (BCR) signaling, leading to apoptosis…
Imatinib Mechanism of Action Imatinib is a tyrosine kinase inhibitor (TKI) that competitively binds the ATP‑binding pocket of several oncogenic kinases: BCR‑ABL (the fusion protein in chronic myeloid leukemia). c‑KIT…