Lorlatinib
Lorlatinib Lorlatinib is a third‑generation, oral anaplastic lymphoma kinase (ALK) and ROS1 tyrosine‑kinase inhibitor (TKI) with superior central nervous system (CNS) penetration. It is indicated for ALK‑positive non‑small cell lung…
Lorazepam
Lorazepam Mechanism of Action Lorazepam is a benzodiazepine that binds to the benzodiazepine site on the GABA‑A receptor complex, acting as a positive allosteric modulator. This binding increases the frequency…
Loratadine
Loratadine Loratadine is a second‑generation, non‑sedating H₁‑histamine receptor antagonist widely prescribed for allergic rhinitis and urticaria. It inhibits peripheral histamine release without significant CNS penetration, making it a preferred first‑line…
Loqtorzi
I’m sorry, but I couldn’t find any reputable information on a drug named Loqtorzi in major pharmacology references, drug databases, or peer‑reviewed literature. Because the drug does not appear to…
Lopressor
Lopressor Lopressor (metoprolol) is a cardioselective β‑adrenergic antagonist widely used in cardiovascular therapy. Mechanism of Action Lopressor competitively blocks β1‑adrenergic receptors in: Heart: ↓heart rate, ↓contractility, ↓myocardial oxygen demand Peripheral…
Loperamide
Loperamide Mechanism of Action G‑protein coupled μ‑opioid receptor agonist primarily acting in the myenteric plexus of the gut. Inhibits cyclic‑AMP synthesis → reduced chloride secretion in enterocytes → decreased luminal…
Lokelma
Lokelma Lokelma (sodium zirconium cyclosilicate) is an oral potassium‑binding polymer used to lower serum potassium levels in patients with hyperkalemia, including those with chronic kidney disease (CKD) and heart failure.…
Lofexidine
Lofexidine An α₂‑adrenergic agonist approved for the rapid, short‑course management of opioid withdrawal symptoms. Mechanism of Action Selective α₂‑adrenergic receptor agonist that activates pre‑synaptic inhibitory autoreceptors in the locus coeruleus.…
Loestrin 24 Fe
Loestrin 24 Fe Loestrin 24 Fe is a 24‑day combined estrogen‑progestin oral contraceptive that delivers 24 active pills (21 hormones + 3 iron) followed by a 7‑day hormone‑free interval. It is indicated for contraception,…
Lithium
Lithium Mechanism of Action The mood stabilizer Lithium primarily modulates intracellular signaling pathways: Inhibition of phosphatidylinositol (PI) turnover → ↓ IP3/Ca²⁺ release, ↓ neuronal excitability. Augmentation of cyclic AMP (cAMP)…