Metronidazole
Metronidazole Mechanism of Action Metronidazole is a pro‑drug that is reduced in anaerobic organisms and select protozoa by nitroreductase enzymes. Reduction generates radical nitro ions that damage microbial DNA strand…
Metoprolol Succinate
Metoprolol Succinate Mechanism of Action Metoprolol Succinate is a β1‑selective adrenergic antagonist. Binds competitively to β1‑adrenergic receptors in cardiac tissue. Blocks catecholamine‑induced stimulation, ↓ heart rate, contractility, and renin release.…
Metoprolol
Metoprolol Metoprolol is a cardioselective β‑adrenergic (β1) blocker widely used for cardiovascular disease management. Below is a concise, evidence‑based reference card optimized for quick learning and clinical decision‑making. Mechanism of…
Metoclopramide
Metoclopramide Mechanism of Action Metoclopramide is a dopamine D2 receptor antagonist that also blocks 5‑hydroxytryptamine 3 (5‑HT3) receptors in the gastrointestinal tract. Gastro‑intestinal (GI) prokinetic effect: Disinhibition of acetylcholine release…
Methylprednisolone
Methylprednisolone Methylprednisolone is a potent synthetic glucocorticoid used extensively for its anti‑inflammatory and immunosuppressive properties in a wide range of clinical settings. --- Mechanism of Action Glucocorticoid receptor (GR) activation…
Methylphenidate
Methylphenidate Methylphenidate (MPH) is a central nervous system (CNS) stimulant widely employed for attention‑deficit/hyperactivity disorder (ADHD) and narcolepsy. It is available in immediate‑release (IR) and multiple extended‑release (ER) formulations. Mechanism…
Methotrexate
Methotrexate Mechanism of Action Methotrexate is a folate antagonist that competitively inhibits dihydrofolate reductase (DHFR), blocking the conversion of dihydrofolate to tetrahydrofolate. The depletion of tetrahydrofolate hampers de novo purine and…
Methocarbamol
Methocarbamol Methocarbamol is a non‑opioid centrally acting muscle relaxant used primarily for symptomatic relief of muscle spasm‑associated discomfort. Mechanism of Action Central nervous system (CNS) depressant – acts on brain‑stem…
Methimazole
Methimazole Methimazole (brand names: Tapazole, Profactil, Morons) is a thioamide antithyroid medication used primarily for the management of hyperthyroidism. Mechanism of Action Inhibition of thyroid hormone synthesis – Methimazole binds…
Methadone
Methadone Mechanism of Action Mu‑opioid receptor agonist – provides analgesia and substitution therapy through sustained activation of central mu receptors. NMDA receptor antagonist – reduces tolerance and opioid‑induced hyperalgesia. Serotonin…