Nourianz
Nourianz Nourianz is the brand name for inhaled treprostinil (TreoVas), a prostacyclin analog used to treat pulmonary arterial hypertension (PAH). Mechanism of Action Treprostinil is a prostacyclin (IP) receptor agonist.…
Norvasc
Norvasc Mechanism of Action Norvasc (brand name for amlodipine) is a selective dihydropyridine calcium channel blocker that inhibits L‑type Ca²⁺ channels in vascular smooth muscle. Vasodilation → ↓ systemic vascular…
Nortriptyline
Nortriptyline Mechanism of Action Nortriptyline is a tricyclic antidepressant (TCA) that competitively inhibits presynaptic reuptake of norepinephrine and serotonin. It increases synaptic concentrations of these monoamines, enhancing neurotransmission in cortical…
Norflex
Norflex Mechanism of Action Norflex (tizanidine) is a selective α2‑adrenergic receptor agonist. Activates presynaptic α2‑receptors in the spinal cord and brainstem. Inhibits release of excitatory amino acids (glutamate) and decreases…
Norethindrone
Norethindrone Mechanism of Action Norethindrone is a synthetic progestin that mimics the activity of endogenous progesterone. Receptor binding: Selective agonist at the progesterone receptor (PR) in target tissues, particularly the…
Norepinephrine
Norepinephrine Norepinephrine (NE, 1‑methylephedrine‑β‑hydroxy‑β‑2‑orphanol) is an endogenous catecholamine used clinically as a potent α‑adrenergic agonist. It is a first‑line vasopressor in severe hypotension and shock. Mechanism of Action α₁‑adrenergic agonist…
Norco
Norco Norco is a fixed‑ratio combination analgesic containing oxycodone (an opioid agonist) and acetaminophen (an NSAID‑like agent). It is primarily used for moderate‑to‑severe acute pain. Mechanism of Action Oxycodone: Mu‑opioid…
Nivolumab
Nivolumab Nivolumab is a fully human monoclonal antibody (IgG4κ) that targets the programmed death‑1 (PD‑1) receptor on T cells, functioning as a PD‑1 checkpoint inhibitor. It’s widely used in oncology…
Nitrostat
Nitrostat Nitrostat is the brand name for the oral nitrate nitroglycerin, commonly used for the rapid relief of acute anginal episodes and for long‑term management of stable angina. --- Mechanism…
Nitroglycerin
Nitroglycerin Mechanism of Action Nitroglycerin is a nitric oxide (NO) donor that undergoes enzymatic bioactivation (aldoketoreductase) in vascular smooth muscle to release NO. NO activates guanylate cyclase ➜ ↑ cyclic…