Anastrozole Mechanism of Action Anastrozole is a reversible, non‑steroidal aromatase inhibitor that competitively binds the heme moiety of the aromatase enzyme (CYP19A1). It irreversibly blocks the conversion of androstenedione and…
Zytiga Mechanism of Action Zytiga (abiraterone acetate) is a selective, irreversible inhibitor of the enzyme cytochrome P450 17α-hydroxylase/c17,20‑lyase (CYP17). CYP17 inhibition ↓synthesis of androgens in the adrenal cortex, testes, and…
Zyrtec Zyrtec (cetirizine) is a second‑generation, selective H1‑histamine receptor antagonist widely used for allergic rhinitis and chronic urticaria. Below is a concise, SEO‑friendly reference for clinicians and students. --- Mechanism…
Zyprexa Olanzapine (brand name Zyprexa) is a second‑generation (atypical) antipsychotic widely prescribed for schizophrenia, bipolar disorder, and adjunctive use in major depressive disorder. --- Mechanism of Action High‑affinity antagonism at…
Zyloprim Zyloprim is a next‑generation antimicrobial agent that targets bacterial DNA gyrase and topoisomerase IV, offering broad spectrum activity against both Gram‑negative and Gram‑positive organisms. It is approved for use in…
Zykadia Zykadia (capmatinib) is a targeted oral therapy approved for the first‑line treatment of advanced or metastatic non‑small cell lung cancer (NSCLC) harboring MET exon 14 skipping mutations. --- Mechanism of…
Zyflo Zyflo is a brand‑name formulation of 5‑fluorouracil (5‑FU) 5 % topical cream, approved for the treatment of actinic keratosis (AK) and superficial basal‑cell carcinoma (sBCC). --- Mechanism of Action DNA…
Zydelig Zydelig (generic idelalisib) is a potent, oral PI3K‑δ inhibitor approved for treatment of relapsed follicular lymphoma, chronic lymphocytic leukemia (CLL), and marginal zone lymphoma. Mechanism of Action Selective inhibition…
Zurzuvae Mechanism of Action Zurzuvae is a high‑affinity inhibitor of the phosphatidylinositol 3‑kinase δ (PI3Kδ) pathway. By competitively binding to the ATP‑binding pocket of PI3Kδ, it prevents downstream activation of…
Zovirax (acyclovir) Mechanism of Action Selective viral targeting: Acyclovir is a guanine nucleoside analog that requires phosphorylation by viral thymidine kinase to become active. Phosphorylation cascade: Monophosphate → Diphosphate →…