Relafen
Relafen Relafen is a potent, orally available, selective tyrosine‑kinase inhibitor (TKI) that targets key receptor kinases involved in tumor angiogenesis and proliferation. It has been approved for use in patients…
Reglan
Reglan Metoclopramide (brand name Reglan) is a synthetic dopamine‑D₂ receptor antagonist with prokinetic and anti‑emetic properties widely used in gastrointestinal disorders and nausea/vomiting prevention. Mechanism of Action D₂ Receptor Antagonism:…
Reclast
Reclast Mechanism of Action Reclast (zoledronic acid) is a third‑generation nitrogen‑containing bisphosphonate. It binds avidly to hydroxyapatite in bone, becoming incorporated into the bone matrix. When osteoclasts resorb bone, zoledronic…
Rebif
Rebif Rebif (Interferon‑β‑1a) is a recombinant human interferon used primarily for the treatment of relapsing‑remitting multiple sclerosis (RRMS). It modulates the immune response, reduces relapse frequency, and slows disability progression.…
ravulizumab
ravulizumab ravulizumab is a humanized monoclonal antibody that inhibits complement protein C5, providing durable complement blockade for patients with complement‑mediated disorders. Mechanism of Action Targets C5 – binds to the…
Rapamune
Rapamune Rapamune (generic name: sirolimus) is a macrolide immunosuppressant used primarily for the prevention of organ transplant rejection. Its unique mechanism of action as an mTOR (mechanistic target of rapamycin)…
Ranolazine
Ranolazine Mechanism of Action Ranolazine is a late sodium current blocker that reduces the intracellular sodium and calcium overload in myocardial cells. Inhibits the late Na⁺ current (I_Na,L) → ↓…
Ranitidine
Ranitidine Ranitidine (brand name Zantac®) is a competitive antagonist of histamine‑2 (H₂) receptors on gastric parietal cells. It was widely used for acid‑related disorders until the 2020‑2023 recall due to…
Ranexa
Ranexa Mechanism of Action Ranexa (ranolazine) is a late sodium current (late I_Na) inhibitor. Late I_Na inhibition → ↓ intracellular Na⁺ → ↓ Ca²⁺ overload via the Na⁺/Ca²⁺ exchanger. Reduced…
Ramipril
Ramipril Mechanism of Action Ramipril is an angiotensin‑converting enzyme (ACE) inhibitor. Enzyme blockade: Inhibits the conversion of angiotensin I → angiotensin II, a potent vasoconstrictor. Effect on neurohormonal axis: Reduces…