Simethicone

Simethicone Simethicone is a non‑absorbable, silicone‑based antifoaming agent used primarily for relief of gastrointestinal gas symptoms such as bloating, belching, and flatulence. It is available OTC as well as through…

Sildenafil

Sildenafil Sildenafil (brand names: Viagra®, Revatio®) is a selective phosphodiesterase‑5 (PDE5) inhibitor widely used for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Mechanism of Action Selective inhibition of PDE5…

Shingrix

Shingrix _Shingrix_ (RZV) is a recombinant subunit zoster vaccine composed of the VZV glycoprotein‑E antigen and the AS01B adjuvant system. Approved for the prevention of herpes zoster and post‑herpetic neuralgia…

Sevelamer

Sevelamer Sevelamer (brand names Renagel®/Apselos®/Renvela®) is a non‑absorbable, calcium‑free phosphate‑binding polymer approved for treating hyperphosphatemia in patients with chronic kidney disease (CKD) or on dialysis. --- Mechanism of Action Non‑absorbed,…

Sertraline

Sertraline Mechanism of Action Selective serotonin reuptake inhibitor (SSRI): Blocks serotonin (5‑HT) re‑uptake transporter (SERT) in presynaptic neurons. Increases extracellular serotonin concentration in the synaptic cleft, enhancing serotonergic neurotransmission. Secondary…

Seroquel

Seroquel Seroquel (quetiapine) is a second‑generation (atypical) antipsychotic characterized by its balanced affinity for dopamine and serotonin receptors and relatively low propensity for extrapyramidal side effects. Mechanism of Action Dopamine…

Sernivo

Sernivo Sernivo (generic combination: fluticasone furoate 100 µg + umeclidinium bromide 62 µg + vilanterol 25 µg) is a once‑daily inhaled triple‑therapy device used in the maintenance treatment of moderate‑to‑severe asthma and chronic…

Senokot

Senokot Mechanism of Action Senokot contains sennosides A and B, anthraquinone glycosides that are biologically inactive until converted by colonic bacteria into active lactones (rhein and emodin). Stimulation of colonic…

Senna

Senna Mechanism of Action Senna contains the anthraquinone glycosides sennosides A and B. Metabolic activation: In the colon, gut bacteria hydrolyze sennosides into active lactone metabolites (rhein anthrone). Stimulation of…

Semaglutide

Semaglutide Semaglutide is a once‑weekly glucagon‑like peptide‑1 (GLP‑1) receptor agonist approved for type 2 diabetes mellitus (T2DM) and chronic weight management in adults with obesity or overweight/obesity plus at least…