Stelara
Stelara Stelara (ustekinumab) is a fully human IgG1λ monoclonal antibody that selectively targets the p40 subunit shared by interleukin‑12 (IL‑12) and interleukin‑23 (IL‑23). Approved for systemic treatment of moderate‑to‑severe plaque…
Sprycel
Sprycel Sprycel (bosutinib) is a second‑generation tyrosine kinase inhibitor (TKI) that selectively blocks the Src and ABL signaling pathways in Philadelphia chromosome–positive cells. --- Mechanism of Action Dual Src/ABL inhibition:…
Spironolactone
Spironolactone Mechanism of Action Spironolactone is a competitive antagonist of mineralocorticoid receptors in the late distal tubule and collecting duct. It blocks the action of aldosterone, preventing Na⁺ reabsorption and…
Spiriva Respimat
Spiriva Respimat Spiriva Respimat (tiotropium bromide) is a once‑daily inhaled long‑acting muscarinic antagonist (LAMA) formulated in a fine‑mist Respimat inhaler for the maintenance treatment of chronic obstructive pulmonary disease (COPD)…
Spiriva
Spiriva Spiriva (tiotropium bromide) is a long‑acting muscarinic antagonist (LAMA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma. Mechanism of Action Tiotropium competitively blocks muscarinic…
Spinraza
Spinraza --- Mechanism of Action Spinraza is a single-stranded antisense oligonucleotide (ASO) that targets a splice site within intron 7 of the SMN2 pre‑mRNA. The ASO binds to the SMN2…
Spevigo
Spevigo Spevigo (difelikefalin) is a synthetic dipeptide and selective κ‑opioid receptor (KOR) agonist approved for prophylaxis of chemotherapy‑induced nausea and vomiting (CINV). Its unique receptor selectivity minimizes CNS opioid effects…
spesolimab
spesolimab Spesolimab (brand name Spesira in the U.S.) is a humanized monoclonal IgG2 antibody that selectively blocks the interleukin‑36 receptor (IL‑36R). Approved in 2023 for generalized pustular psoriasis (GPP), it…
Sovaldi
Sovaldi Sovaldi (sofosbuvir) is a potent, once‑daily, orally active, nucleotide analog prodrug approved for the treatment of chronic hepatitis C virus (HCV) infection. Mechanism of Action Retro‑viral polymerase inhibitor 4,…
Sotalol
Sotalol Sotalol is a non‑selective β‑adrenergic blocker that also possesses class III anti‑arrhythmic properties. It is indicated for the prevention of arrhythmias in patients with atrial fibrillation/flutter and ventricular tachyarrhythmias. Mechanism…