Alunbrig
Alunbrig Alunbrig (generic name: alunbrigitin) is a humanized monoclonal antibody that targets the programmed death‑ligand 1 (PD‑L1) expressed on tumor cells and antigen‑presenting cells. It is currently approved for the…
Alprolix
Alprolix Alprolix is a recombinant human growth hormone (somatropin) produced via recombinant DNA technology. It is administered subcutaneously and is approved for treating growth hormone deficiency in children and adults,…
Alecensa
Alecensa Alecensa (generic afatinib) is an irreversible epidermal growth factor receptor (EGFR) tyrosine‑kinase inhibitor (TKI) indicated for patients with metastatic or unresectable non‑small cell lung cancer (NSCLC) harboring EGFR‑exon 19 deletions or…
Alprazolam
Alprazolam Mechanism of Action Alprazolam is a benzodiazepine that potentiates inhibitory neurotransmission. Enhances the activity of the γ‑aminobutyric acid (GABA)‑A receptor complex. Increases chloride ion influx, hyperpolarizing neuronal membranes. Produces…
Allopurinol
Allopurinol Allopurinol is the cornerstone xanthine oxidase inhibitor used to manage chronic gout and hyperuricemia, prevent nephrolithiasis, and control uric acid production in tumor lysis syndrome. --- Mechanism of Action…
Aldactone
Aldactone (Spironolactone) Mechanism of Action Spironolactone is a non‑steroidal potassium‑sparing diuretic that acts primarily by antagonizing aldosterone at the epithelial sodium channel (ENaC) in the distal nephron. Aldosterone blockade →…
Albuterol
Albuterol Albuterol (also known as salbutamol) is a short‑acting β₂‑adrenergic agonist widely used as an inhaled bronchodilator for pulmonary conditions. Mechanism of Action β₂‑Receptor Agonist β₂ receptors on bronchial smooth‑muscle…
Acyclovir
Acyclovir Mechanism of Action Selective activation by viral thymidine kinase to acyclovir monophosphate (viral specific). Host cellular kinases convert it to the triphosphate form. The triphosphate competitively inhibits viral DNA…
Ajovy
Ajovy Ajovy® (galcanezumab‑mtsch) is a humanized monoclonal antibody that selectively targets the calcitonin gene‑related peptide (CGRP) ligand. It is approved for the preventive treatment of migraine in adults, both episodic…
Aimovig
Aimovig Aimovig (erenumab‑bmyq) is a fully human monoclonal antibody that selectively targets the calcitonin gene‑related peptide (CGRP) receptor, offering a novel preventive therapy for migraine. Approved by the FDA (2018)…