Triamterene

Triamterene Triamterene is a potassium‑sparing diuretic commonly used in combination with loop or thiazide diuretics to enhance natriuresis while mitigating potassium loss. Mechanism of Action Triamterene competitively inhibits the epithelial…

Triamcinolone

Triamcinolone --- Mechanism of Action Triamcinolone is a synthetic glucocorticoid that exerts its therapeutic effects by Binding to cytoplasmic glucocorticoid receptors → complex translocates to the nucleus. Modulating gene transcription:…

Tretinoin

Tretinoin Tretinoin (all-trans-retinoic acid) is a retinoid, the first‑in‑class prescription topical therapy for acne vulgaris, and a nucleic‑acid analog used orally for acute promyelocytic leukemia (APL). It is also employed…

Tresiba

Tresiba Mechanism of Action Tresiba is a long‑acting insulin analog (glargine U300) that delivers a steady‑state release of insulin over ~72 h. It contains a glutamic‑acryloyl substitution at the B29 residue…

Tremfya

Tremfya Mechanism of Action Tremfya (guselkumab) is a human monoclonal IgG1κ antibody that selectively binds the p19 subunit of interleukin‑23 (IL‑23). Inhibits IL‑23 signaling to T‑helper 17 cells, reducing pro‑inflammatory…

Trelstar

Trelstar Trelstar (brand name for trypinase – a selective trypsin and elastase inhibitor) is a recently approved therapeutic agent for the treatment of acute pancreatitis (AP). It is developed by…

Trelegy Ellipta

Trelegy Ellipta Mechanism of Action Trelegy Ellipta is a fixed‑dose combination of three bronchodilators: Fluticasone furoate – an inhaled glucocorticoid that suppresses airway inflammation by inhibiting NF‑κB‑mediated cytokine production. Umeclidinium…

Treanda

Treanda Treanda (10 % Intravenous Immunoglobulin [IVIG] – IgG) GSK’s recombinant IgG preparation used for immunomodulation in acute and chronic immune‑mediated disorders. Mechanism of Action Fcγ Receptor (FcγR) blockade – saturated…

Trazodone

Trazodone Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) widely used for depression and insomnia. Mechanism of Action Serotonin Modulation – Inhibits serotonin reuptake via the 5‑HT₂A receptor, increasing…

trastuzumab deruxtecan

trastuzumab deruxtecan Trastuzumab deruxtecan (brand name Enhertu) is a HER2‑targeted antibody‑drug conjugate (ADC) approved for the treatment of HER2‑positive solid tumors, most notably metastatic breast cancer and metastatic gastric/GEJ cancer.…