Archives: Drug Cards

Venclexta (Venetoclax) Mechanism of Action Potent, selective inhibitor of BCL‑2 – binds the BH3 domain of BCL‑2, displacing pro‑apoptotic proteins (BAX, BAK) and triggering mitochondrial outer‑membrane permeabilization. Overcomes anti‑apoptotic signaling…

Velcade Velcade® (generic name bortezomib) is a reversible, non‑competitive proteasome inhibitor approved for the treatment of plasma‑cell malignancies. The drug’s high specificity for the β5 subunit of the 26S proteasome…

Vasotec Vasotec is the brand name for lisinopril, a potent angiotensin‑converting enzyme (ACE) inhibitor used widely in cardiovascular therapy. --- Mechanism of Action Inhibits ACE: Blocks the conversion of angiotensin…

Vascepa Vascepa (icsapent ethyl) is a highly purified ethyl ester of eicosapentaenoic acid (EPA), classified as a fish‑oil derivative. It is indicated for triglyceride (TG) lowering in patients at high…

Varenicline Mechanism of Action Varenicline is a partial agonist at neural α4β2 nicotinic acetylcholine receptors (nAChRs), the primary binding sites for nicotine in the brain. By binding to these receptors,…

Vanos Vanos is a novel, once‑daily, oral pharmacologic agent approved for the management of moderate to severe plaque psoriasis and associated psoriatic arthritis. It is classified as a selective, covalent…

Vancomycin Vancomycin is a glycopeptide antibiotic that has become the cornerstone of therapy for many gram‑positive infections, especially those caused by methicillin‑resistant Staphylococcus aureus (MRSA). Mechanism of Action Inhibits bacterial…

Vamorolone Vamorolone is a novel, orally‑administered, synthetic neuro‑steroid that selectively antagonizes the harmful, genomic actions of glucocorticoids while preserving anti‑inflammatory efficacy. --- Mechanism of Action Vamorolone engages the glucocorticoid receptor…

Valtrex Valtrex (valacyclovir) is a prodrug of acyclovir, extensively used in the treatment and suppression of herpes simplex virus (HSV) and varicella‑zoster virus (VZV) infections. Mechanism of Action Cell‑entry: Valacyclovir…

Valtoco Valtoco (generic valproic acid 400 mg) is an FDA‑approved antiepileptic drug (AED) widely used for seizure control and bipolar mood stabilization. It is a versatile, high‑yield medication, especially useful when…