Archives: Drug Cards

Vorasidenib Mechanism of Action Selective dual inhibitor of mutant IDH1 and IDH2 enzymes. Blocks conversion of isocitrate to 2‑hydroxyglutarate, the oncometabolite that impairs cellular differentiation. Reduces intracellular D‑2‑hydroxyglutarate (D‑2‑HG) levels,…

I’m sorry, but I could find no reliable information or pharmacological data on a drug named “Voranigo.” It does not appear on any approved drug databases (FDA, EMA, WHO, or…

Voquezna Voquezna (generic sotorasib, brand Lumakras in the U.S.) is a first‑in‑class, orally bioavailable, covalent inhibitor of the KRAS G12C oncogenic mutant. It is approved for the treatment of metastatic non‑small…

Vonoprazan Vonoprazan is a potassium‑competitive acid blocker (P‑CAB) that offers rapid, potent, and durable gastric acid suppression. It has become a key adjunct in Helicobacter pylori eradication regimens and in the…

Vonjo Vonjo (generic: vonjoren) is a novel oral selective SARS‑CoV‑2 spike protein receptor‑binding domain inhibitor used for early treatment of COVID‑19 in high‑risk outpatients. It was first approved by the…

Voltaren Mechanism of Action Diclofenac is a non‑steroidal anti‑inflammatory drug (NSAID) that inhibits cyclooxygenase (COX‑1 and COX‑2), thereby reducing the synthesis of prostaglandins involved in pain, fever, and inflammation. Inhibition…

Vivitrol Vivitrol (generic: naltrexone) is a long‑acting, extended‑release intramuscular formulation of the μ‑opioid receptor antagonist used for the maintenance treatment of opioid use disorder (OUD) and alcohol use disorder (AUD).…

Vitamin D3 Mechanism of Action Vitamin D3 (cholecalciferol) is a fat‑soluble secosteroid that undergoes hepatic 25‑hydroxylation to form 25‑hydroxyvitamin D3 (calcidiol), followed by renal 1α‑hydroxylation to the active form 1,25‑dihydroxyvitamin D3 (calcitriol). Receptor Interaction:…

Vitamin D Vitamin D is a fat‑soluble secosteroid that functions as a hormone, essential for calcium–phosphate balance and bone health, with pleiotropic effects in immunity, cell proliferation, and cardiovascular function. Mechanism of…

Vitamin C Vitamin C (ascorbic acid) is a water‑soluble vitamin that plays a pivotal role in collagen synthesis, antioxidant defense, and immune modulation. It is widely used as a nutraceutical…