Abiraterone

Abiraterone Abiraterone (Abiraterone acetate) is a selective, irreversible inhibitor of the 17α‑hydroxylase/17,20‑lyase (CYP17) enzyme, used primarily for the management of metastatic castration‑resistant prostate cancer (mCRPC). --- Mechanism of Action Inhibition…

Abilify

Abilify Abilify (generic name aripiprazole) is a second‑generation antipsychotic widely used in psychiatric practice. It functions as a partial agonist at dopamine D₂ receptors and 5‑HT₁A receptors, while acting as…

Abecma

Abecma Abecma (idecabtagene vicleucel) is a bispecific chimeric antigen receptor (CAR) T‑cell therapy engineered to target B‑cell maturation antigen (BCMA) on malignant plasma cells. It is approved for adults with…

Azithromycin

Azithromycin Azithromycin is a macrolide antibiotic widely used for respiratory, skin, and sexually transmitted infections. It is known for its long half‑life and excellent tissue penetration, allowing short‑course regimens. ---…

Azathioprine

Azathioprine Mechanism of Action Azathioprine is a pro‑drug that is converted to 6‑mercaptopurine (6-MP). 6‑MP interferes with purine synthesis, inhibiting DNA and RNA synthesis in rapidly dividing immune cells. Conversion…

Atorvastatin

Atorvastatin --- Mechanism of Action Competitive inhibitor of HMG‑CoA reductase, the rate‑limiting enzyme of endogenous cholesterol biosynthesis in the liver. Down‑regulates hepatic LDL‑receptor transcription → ↑ LDL‑receptor density → enhanced…

Atomoxetine

Atomoxetine Atomoxetine (brand name Strattera®) is a selective norepinephrine reuptake inhibitor (NRI) approved primarily for the treatment of attention‑deficit/hyperactivity disorder (ADHD) in children, adolescents, and adults. Unlike stimulants, it does…

Atenolol

Atenolol Atenolol is a selective β₁‑adrenergic receptor blocker commonly used for cardiovascular disorders. The drug’s low lipophilicity limits central nervous system penetration, making it a preferred choice when cognitive side‑effects…

Aripiprazole

Aripiprazole Aripiprazole is a second‑generation antipsychotic distinguished by its partial agonist activity at dopamine D₂/D₃ receptors and serotonin 5‑HT₁A receptors, with antagonism at 5‑HT₂A. It is used extensively for schizophrenia,…

Apixaban

Apixaban Apixaban is a direct oral anticoagulant (DOAC), widely recognized as a selective, reversible Factor Xa inhibitor used in thromboprophylaxis and antithrombotic therapy. Mechanism of Action Selective inhibition of activated…