Darzalex
Darzalex Darzalex (daratumumab) is a human IgG1κ monoclonal antibody targeting CD38, approved for treatment of multiple myeloma. It is available as an intravenous infusion (Darzalex) and a subcutaneous (SC) formulation…
Dapagliflozin
Dapagliflozin Dapagliflozin is a selective sodium‑glucose co‑transporter 2 (SGLT‑2) inhibitor indicated for the management of type 2 diabetes mellitus and for improving cardiovascular and renal outcomes in high‑risk patients. Mechanism of Action…
Dabigatran
Dabigatran Dabigatran (brand name Pradaxa) is an orally‑active, direct thrombin (Factor IIa) inhibitor used primarily for stroke prevention in non‑valvular atrial fibrillation and for the treatment and secondary prevention of…
Cymbalta
Cymbalta Mechanism of Action Cymbalta (duloxetine) is a serotonin‑norepinephrine reuptake inhibitor (SNRI). Inhibits reuptake transporters: Serotonin transporter (SERT) – 65–84 % relative potency. Norepinephrine transporter (NET) – 20–30 % relative potency. Resulting…
Cyclobenzaprine
Cyclobenzaprine Cyclobenzaprine is a centrally acting skeletal‑muscle relaxant widely prescribed for short‑term relief of acute musculoskeletal spasms. Mechanism of Action Acts primarily in the central nervous system (CNS) rather than…
Cyanocobalamin
Cyanocobalamin A synthetic form of vitamin B12 used primarily to correct deficiency states and for various hematologic and neurologic disorders. Mechanism of Action Reduces methylmalonic acid (MMA) and homocysteine by functioning…
Crestor
Crestor Mechanism of Action Rosuvastatin is a highly potent, selective inhibitor of 3‑hydroxy‑3‑methyl‑glutaryl‑CoA (HMG‑CoA) reductase, the rate‑limiting enzyme in hepatic cholesterol synthesis. By blocking this step, Crestor reduces intracellular cholesterol,…
Cosentyx
Cosentyx Cosentyx (secukinumab) is a fully human IgG1κ monoclonal antibody that selectively neutralizes interleukin‑17A (IL‑17A). Approved for plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, it represents a pivotal advance in…
Coreg
Coreg Mechanism of Action Coreg (carvedilol) is a non‑selective β‑adrenergic blocker with additional α₁‑blocking activity and antioxidant properties. β‑blockade: ↓ heart rate, myocardial contractility, and renin release. α₁‑blockade: ↓ systemic…
Colchicine
Colchicine --- Mechanism of Action Colchicine exerts its therapeutic effect primarily by binding tubulin and inhibiting microtubule polymerization. ↓ Neutrophil chemotaxis, adhesion, and degranulation. ↓ Cytokine release (IL‑1β, TNF‑α) by…