Diazepam
Diazepam Mechanism of Action Diazepam is a benzodiazepine that potentiates the inhibitory neurotransmitter gamma‑aminobutyric acid (GABA). It binds to a specific allosteric site on the GABA_A receptor complex, increasing chloride…
Diastat
Diastat Mechanism of Action Diastat is a dual‑acting α1‑adrenergic antagonist that also inhibits the Rho‑kinase pathway, producing potent vasodilation. α1‑Adrenergic blockade → decreases vascular smooth‑muscle contraction, lowering peripheral resistance. Rho‑kinase…
Diacomit
Diacomit Diacomit (granisetron dihydrochloride) is a potent, orally and parenterally administered 5‑HT₃ receptor antagonist used primarily for the prevention of chemotherapy‑induced nausea and vomiting (CINV) and postoperative nausea/vomiting (PONV). Mechanism…
Dextrose
Dextrose Mechanism of Action Dextrose (glucose‑6‑phosphate) is the primary energy substrate for all mammalian cells. Rapid uptake by GLUT‑4 transporters on muscle and adipose cells and by GLUT‑1 on the…
Dextromethorphan
Dextromethorphan Dextromethorphan (DXM) is a widely used over‑the‑counter cough suppressant. It is a chiral β‑amino alcohol that acts as a non‑competitive antagonist of the N‑methyl‑D‑aspartate (NMDA) receptor and an agonist…
Dextroamphetamine
Dextroamphetamine Mechanism of Action Neurotransmitter Release Agonist – ↑ synaptic dopamine (DA) and norepinephrine (NE) by reversing the dopamine transporter (DAT) and norepinephrine transporter (NET), leading to increased synaptic monoamine…
Dexlansoprazole
Dexlansoprazole Mechanism of Action The dual‑delayed‑release formulation delivers two distinct pharmacokinetic profiles, ensuring both early and sustained plasma levels. Dexlansoprazole irreversibly inhibits the gastric H⁺/K⁺ ATPase (proton pump) on parietal‑cell…
Dexilant
Dexilant Mechanism of Action Dexilant (dexlansoprazole) is a proton pump inhibitor (PPI) that irreversibly binds to the hydrogen‑potassium ATPase (H⁺/K⁺‑ATPase) on the parietal cell membrane. This blockage prevents the final…
Dexamethasone
Dexamethasone Dexamethasone is a potent synthetic glucocorticoid with anti‑inflammatory, immunosuppressive, and metabolic effects. It is widely used in clinical practice for a spectrum of conditions, from endocrine disorders to oncologic…
Deutetrabenazine
Deutetrabenazine A deuterated analog of tetrabenazine approved for the treatment of tardive dyskinesia and Huntington disease chorea. It offers improved metabolic stability while maintaining the same mechanism of action as…