Enoxaparin
Enoxaparin Enoxaparin is a low‑molecular‑weight heparin (LMWH) used for the prevention and treatment of venous thromboembolism (VTE) and various arterial thrombotic conditions. Mechanism of Action Selective inhibition of factor Xa:…
Enbrel
Enbrel Enbrel (etanercept) is a recombinant human fusion protein that functions as a TNF‑α inhibitor. It is marketed as a biologic DMARD for the treatment of several immune‑mediated diseases. Mechanism…
Enalapril
Enalapril Enalapril is a prodrug of the active enalaprilat that functions as a potent angiotensin‑converting enzyme (ACE) inhibitor. It is widely prescribed for hypertension, chronic heart failure, and post‑myocardial infarction…
Empaveli
Empaveli Empaveli (inotersen) is a synthetic antisense oligonucleotide indicated for the treatment of progressive chronic‑maturity onset diabetes of the young type 1 (P‑MODY1), a rare inherited amyloidosis. It is administered…
Empagliflozin
Empagliflozin Mechanism of Action Selective SGLT2 inhibition in the proximal tubule → blocks ~90 % of glucose reabsorption. Glucosuria (≈–60 mg/kg/day) decreases plasma glucose independent of insulin. Secondary effects: mild natriuresis, osmotic…
Emgality
Emgality Emgality (galcanezumab‑tmca) is a humanized monoclonal antibody that selectively targets the calcitonin gene‑related peptide (CGRP) pathway for migraine prevention. Mechanism of Action Selective CGRP ligand inhibition – Galcanezumab binds…
Eliquis
Eliquis Brand Name: Eliquis Generic: apixaban Class: Direct oral anticoagulant (DOAC) – Factor Xa inhibitor --- Mechanism of Action Selective, reversible inhibition of the active site of cofactor‑dependent Factor Xa.…
Eligard
Eligard Mechanism of Action Eligard delivers a local dose of levonorgestrel (LNG), a synthetic progestin, directly into the uterine cavity. The high intrauterine concentration of LNG produces several pharmacologic effects…
Elevidys
Elevidys Elevidys (valoctocogene roxaparvovec) is the first FDA‑approved gene‑therapy treatment for spinal muscular atrophy (SMA). It delivers a functional copy of the SMN1 gene via an adeno‑associated virus serotype 9…
Elavil
Elavil --- Mechanism of Action Elavil (amitriptyline) is a first‑generation tricyclic antidepressant (TCA). Neurotransmitter inhibition – blocks presynaptic reuptake of norepinephrine (NE) and serotonin (5‑HT), increasing their synaptic concentrations. Receptor…