Epoetin Alfa Mechanism of Action Epoetin Alfa is a recombinant form of human erythropoietin (EPO). Binds to the EPO receptor (EPOR) on erythroid progenitor cells in the bone marrow. Activates…
Eplerenone Mechanism of Action Eplerenone is a selective mineralocorticoid receptor antagonist (MRA). It competitively blocks aldosterone binding to the mineralocorticoid receptor in the distal nephron and vasculature. This inhibition reduces…
EpiPen EpiPen is the brand name for autoinjectors containing epinephrine, a potent adrenergic agonist used for the rapid relief of anaphylaxis and severe allergic reactions. This drug card summarizes its…
Epinephrine Mechanism of Action Epinephrine is a non‑selective adrenergic agonist that stimulates α‑ and β‑adrenergic receptors via the G‑protein–mediated cascade. α‑1 adrenoceptor activation → vascular smooth‑muscle contraction → ↑ systemic…
Epidiolex Mechanism of Action Epidiolex is a purified, purified‑quality cannabidiol (CBD) formulation. Its antiepileptic effects are mediated through a multifaceted, low‑potency interaction with the endocannabinoid system and several non‑cannabinoid targets:…
Enzalutamide Mechanism of Action Enzalutamide is a second‑generation, non‑steroidal antagonist that binds with high affinity to the ligand‑binding domain of the androgen receptor (AR). It blocks AR nuclear translocation, DNA…
Entyvio Entyvio (vedolizumab) is a humanized anti‑α4β7 integrin monoclonal antibody used primarily for moderate‑to‑severe ulcerative colitis (UC) and Crohn’s disease (CD). Mechanism of Action Targets α4β7 integrin on gut‑homing T‑lymphocytes.…
Entresto Entresto (generic: sacubitril/valsartan) is a fixed‑ratio oral combination of a neprilysin inhibitor and an angiotensin II receptor blocker (ARB), approved for the treatment of heart failure with reduced ejection…
Entecavir Entecavir (brand name: Baraclude®) is a potent, low‑genetic‑barrier nucleoside analog used primarily for chronic hepatitis B (HBV) infection. Mechanism of Action Synthetic guanine nucleoside analog that requires intracellular phosphorylation to…
Enspryng Mechanism of Action Enspryng is a once‑weekly, long‑acting semaglutide formulation that mimics the incretin hormone glucagon‑like peptide‑1 (GLP‑1). It binds to the GLP‑1 receptor on pancreatic β‑cells, enhancing glucose‑stimulated…